Evidence map›Paper›PMID 41486904›Full record

ArticleAnnals of medicine2026

Machine learning for screening laryngopharyngeal reflux symptoms in college students: a cross-sectional study.

Shuang Li, Guoji Wang, Haixian Guo, Jinzhang Cheng, Dan Yu

Abstract read
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Global burden of Laryngopharyngeal reflux disease: a systematic review of epidemiology, cost-burden and awareness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuang LiDepartment of Otolaryngology-Head and Neck Surgery, The Second Hospital of Jilin University, Changchun, Jilin Province, P.R. China.
Guoji WangSchool of Mathematics and Statistics, Changchun University of Technology, Changchun, Jilin Province, P.R. China.
Haixian GuoDepartment of Otolaryngology-Head and Neck Surgery, The Second Hospital of Jilin University, Changchun, Jilin Province, P.R. China.
Jinzhang ChengDepartment of Otolaryngology-Head and Neck Surgery, The Second Hospital of Jilin University, Changchun, Jilin Province, P.R. China.
Dan YuDepartment of Otolaryngology-Head and Neck Surgery, The Second Hospital of Jilin University, Changchun, Jilin Province, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

bckgroundLaryngopharyngeal reflux (LPR) is a widespread global health issue. Its recurring symptoms and impact on quality of life create significant economic burdens for individuals and society. To examine the links between lifestyle, diet, and LPR symptoms (LPRS) in college students, and to build an LPRS screening model using a Genetic Algorithm (GA)-Stacking method. PATIENTS AND

methodsA cross-sectional study of 502 undergraduates from 21 universities in Jilin Province, China, using an electronic questionnaire. LPRS were assessed via the Reflux Symptom Index (RSI). Associations were analyzed with multiple methods, and a GA-Stacking screening model was developed.

resultsLPRS prevalence was 50.20% (252/502). Significant risk factors included frequent fried food consumption (OR: 1.89; 95% CI, 1.35-2.64), late-evening meals (OR: 2.15; 95% CI, 1.54-3.01), and low physical activity (OR: 1.72; 95% CI, 1.23-2.41). The GA-Stacking model performed well, with a recall of 0.909, accuracy of 0.927, and AUC of 0.96 (95% CI, 0.94-0.98).

conclusionsModifiable factors like fried food intake and meal timing are strongly linked to LPRS in students. The GA-Stacking model effectively identifies high-risk individuals for early intervention, highlighting the role of lifestyle changes and informing targeted health strategies.

Indexed as

Laryngopharyngeal RefluxMachine LearningMass ScreeningStudentsAdolescentAdultChinaCross-Sectional StudiesDietExerciseFemaleHumansLife StyleMalePrevalenceQuality of LifeDietary patternsgastroesophageal reflux diseaseGenetic Algorithm–Stackinglaryngopharyngeal reflux symptomslifestyle behaviours

Identifiers

PMID41486904
PMCPMC12777997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.