Evidence map›Paper›PMID 41486610›Full record

ArticleEpidemiology and psychiatric sciences2026

Risk of depressive and anxiety disorders in young adults with disabilities: a nationwide cohort study in South Korea.

Hwa-Young Lee, In Young Cho, Dong Wook Shin, Kyung-Do Han

Abstract read
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Article in Epidemiology and psychiatric sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hwa-Young LeeGraduate School of Public Health and Healthcare Management, The Catholic University of Korea, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-2591-1436
In Young ChoDepartment of Family Medicine and Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Dong Wook ShinDepartment of Family Medicine and Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-8128-8920
Kyung-Do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough often associated with ageing, disability is becoming increasingly prevalent among young adults. While disability can pose a substantial psychological burden for young adults on critical pathways to establish the foundations for their future, the mental health risks faced by this population remain underexplored.

aimsThis study aimed to (1) assess the association between disability - including its presence, severity and type - and the risk of depressive and anxiety disorders, and (2) examine whether this association varies across sociodemographic factors, health behaviours and comorbidities in a young adult population.

methodsWe conducted a population-based cohort study using linked data from the National Disability Registry and the National Health Insurance Database of South Korea. A total of 6,058,290 individuals aged 20-39 years who underwent health check-ups between 2009 and 2012 were followed through 2022. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) for depressive and anxiety disorders.

resultsIndividuals with disabilities had significantly higher risks of depressive (aHR: 1.58, 95% CI: 1.55-1.60) and anxiety disorders (aHR: 1.50, 95% CI: 1.42-1.59). Increased risks were consistently observed across various disability types with the highest risk observed for mental health-related disabilities in depression (aHR: 4.98, 95% CI 4.62-5.37) and epilepsy-related disabilities in anxiety disorders (aHR: 12.05, 95% CI 8.73-16.63). Subgroup analyses revealed stronger associations among individuals in their 20s, low-income groups, non-smokers and those abstaining from alcohol, compared to their respective counterparts.

conclusionsYoung adults with disabilities, a population that has been relatively overlooked in policy discussions, warrant greater policy attention in relation to their mental health.

Indexed as

Anxiety DisordersDepressive DisorderPersons with DisabilitiesAdultCohort StudiesComorbidityFemaleHumansMaleRepublic of KoreaRisk FactorsYoung Adultcommon mental disordersepidemiologysocial factorssurvival analysisyoung adults

Identifiers

PMID41486610
PMCPMC12816932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.