Evidence map›Paper›PMID 41486443›Full record

ArticleInfection & chemotherapy2025

Role of Treatment with Remdesivir on the Early Readmission of Patients Affected by Nosocomial Coronavirus Disease 2019.

Lucio Boglione, Valentina Dodaro, Roberto Rostagno, Roberta Moglia, Marco Cantone, Younes Harouny, Federica Poletti

Abstract read
In one paragraph

Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucio BoglioneDepartment of Translational Medicine, University of Eastern Piedmont, Novara, Italy. lucio.boglione@uniupo.it.ORCID https://orcid.org/0000-0001-8326-4930
Valentina DodaroDepartment of Medical Sciences, University of Turin, Turin, Italy.ORCID https://orcid.org/0009-0006-5978-258X
Roberto RostagnoUnit of Infectious Diseases, Saint Andrea Hospital, Vercelli, Italy.ORCID https://orcid.org/0000-0002-4428-8275
Roberta MogliaUnit of Infectious Diseases, Saint Andrea Hospital, Vercelli, Italy.ORCID https://orcid.org/0009-0002-3560-3963
Marco CantoneUnit of Infectious Diseases, Saint Andrea Hospital, Vercelli, Italy.ORCID https://orcid.org/0009-0007-7130-8490
Younes HarounyUnit of Infectious Diseases, Saint Andrea Hospital, Vercelli, Italy.ORCID https://orcid.org/0009-0000-8299-3015
Federica PolettiUnit of Infectious Diseases, Saint Andrea Hospital, Vercelli, Italy.ORCID https://orcid.org/0009-0007-5399-2874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe patients affected by hospital-acquired coronavirus disease 2019 (HA-COVID-19) who were readmitted in hospital within 60 days had worse prognosis and mortality. In this study the aim was the assessment of early readmission rate in HA-COVID-19 and the role of remdesivir treatment. MATERIALS AND

methodsThis observational retrospective study included patients with HA-COVID-19 hospitalized in different wards between Jan 2021 and Mar 2022. Early readmission rate was determined. A multivariate logistic regression was made to determine the predictive factors for re-hospitalization.

resultsA total of 190 patients with a confirmed diagnosis of HA-COVID-19 were included. Early readmission was documented in 22 patients (11.6%) with a consequent mortality rate of 22.7%. In multivariate analysis, the following factors were predictive of readmission: chronic pulmonary disease (odds ratio [OR], 3.187; 95% confidence interval [CI], 2.145-11.228;

conclusionReadmission cumulative rate was about one tenth with higher mortality. The remdesivir use in the first hospitalization leads to significant reduction in the odds of readmission.

Indexed as

Antiviral therapyReadmissionRemdesivirSARS-CoV-2, nosocomial, COVID-19

Identifiers

PMID41486443
PMCPMC12802054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.