ArticleInfection & chemotherapy2025
Evidence of Possible Mucormycosis Coinfection, Detected by Plasma Mucorales PCR, in Patients with Proven or Probable Aspergillosis.
Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundData on coinfection with MATERIALS AND
methodsAdult patients with proven or probable aspergillosis who consented to blood sampling were prospectively enrolled at a tertiary hospital between January 2017 and April 2020, and again between June 2023 and February 2025. Aspergillosis was classified according to the European Organization for Research and Treatment of Cancer/Mycosis Study Group (EORTC/MSG) criteria. Plasma 18S PCR was performed to detect
resultsA total of 82 patients (28 with proven and 54 with probable aspergillosis) were analyzed. No Mucorales were detected in sterile or non-sterile cultures. Among the 28 patients with proven aspergillosis, 4 (14.3%) showed evidence of mucormycosis coinfection: 2 had a positive Mucorales-specific PCR result, and 2 had positive PCR results for both
conclusionApproximately 10-20% of patients with proven or probable aspergillosis had molecular evidence of possible mucormycosis coinfection, as detected by plasma Mucorales PCR.
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