Evidence map›Paper›PMID 41486141›Full record

ReviewJournal of medical case reports2026

Management of heterotopic cervical pregnancy: a case report and review of the literature.

Giulia Principi, Massimo M Salvatori, Fernando Ficarola, Giovanni Larciprete

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giulia PrincipiDepartment of Obstetrics and Gynecology, Martini Hospital - ASL "Città di Torino", Via Tofane, 71, 10141, Turin, Italy.
Massimo M SalvatoriDepartment of Obstetrics and Gynecology, Ospedale Fatebenefratelli Isola Tiberina, Roma, Via di Ponte Quattro Capi, 39, 00186, Rome, Italy.
Fernando FicarolaResearch Unit of Gynecology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Rome, Italy.
Giovanni LarcipreteDepartment of Obstetrics and Gynecology, Ospedale Fatebenefratelli Isola Tiberina, Roma, Via di Ponte Quattro Capi, 39, 00186, Rome, Italy. giovanni.larciprete@fbf-isola.it.ORCID http://orcid.org/0000-0003-3520-206X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeterotopic cervical pregnancy is an extremely rare condition, defined by the simultaneous presence of an intrauterine gestation and an ectopic gestation located in the uterine cervix. Cervical pregnancies are associated with a high risk of severe hemorrhage owing to the close proximity of the trophoblastic tissue to the uterine blood vessels. Early diagnosis is often challenging, as clinical symptoms are frequently absent or nonspecific. Currently there are no standardized management guidelines for coexisting intrauterine and cervical pregnancies; treatment decisions depend largely on the patient's desire to continue the intrauterine pregnancy and the clinical expertise of the healthcare team. CASE PRESENTATION: We report the case of a 31-year-old primigravida of Sri Lankan ethnicity with a spontaneous heterotopic pregnancy, who presented at 6 + 5 weeks of gestation with vaginal bleeding. Her medical and surgical history were unremarkable. Transvaginal ultrasound revealed a viable intrauterine pregnancy coexisting with a viable cervical ectopic pregnancy. Given the acute bleeding and the patient's wish to preserve the intrauterine pregnancy, surgical management was chosen. Ultrasound-guided cervical curettage with preemptive bilateral cervical suturing was performed, achieving an effective hemostasis. At 16 weeks, a Shirodkar cerclage was placed due to cervical shortening. The pregnancy progressed without complications, and a healthy newborn was delivered via cesarean section at 38 + 6 weeks of gestation.

conclusionGiven the rarity and potentially life-threatening nature of heterotopic cervical pregnancy, the dissemination of clinical experiences is essential to improve diagnostic accuracy and inform management strategies. This case highlights the importance of early recognition and tailored surgical intervention. Ultrasound-guided evacuation with targeted cervical suturing effectively controlled the hemorrhage while preserving the intrauterine pregnancy, whilst second-trimester cerclage addressed cervical shortening. Our experience supports a conservative and individualized approach guided by patient preferences, clinical stability, and multidisciplinary expertise as a viable strategy for optimizing maternal and fetal outcomes in this rare and high-risk condition.

Indexed as

Cerclage, CervicalCervix UteriPregnancy, EctopicPregnancy, HeterotopicUterine HemorrhageAdultFemaleHumansPregnancySri LankaUltrasonography, PrenatalCase reportCervical pregnancyExtrauterine gestationHeterotopicShirodkar cervical cerclage

Identifiers

PMID41486141
PMCPMC12777257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.