Evidence map›Paper›PMID 41486113›Full record

ArticleBMC psychiatry2026

Profiling Chinese children with symptoms of SpLD, ADHD, or ASD: a transdiagnostic and biopsychosocial study.

Duo Liu, Ziqian Wei, Urs Maurer, Kevin Kien Hoa Chung, Jesus Alfonso D Datu, Liory Fern-Pollak, Taeko Wydell, Winnie Wan-Yee Tso, Fenghua Sun, Lirong Luo and 4 more

Erratum issuedAbstract read
In one paragraph

Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Duo Liu *Department of Special Education and Counselling, The Education University of Hong Kong, 10 Lo Ping Road, Hong Kong SAR, China. duoliu@eduhk.hk.ORCID 0000-0002-2352-2616
Ziqian Wei *Department of Special Education and Counselling, The Education University of Hong Kong, 10 Lo Ping Road, Hong Kong SAR, China.ORCID 0009-0005-1352-887X
Urs MaurerDepartment of Psychology, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-4156-8597
Kevin Kien Hoa ChungDepartment of Early Childhood Education, The Education University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8105-7361
Jesus Alfonso D DatuFaculty of Education, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8790-1113
Liory Fern-PollakDepartment of Psychology and Human Development, University College London, London, UK.
Taeko WydellDepartment of Life Sciences, Brunel University London, London, UK.ORCID 0000-0001-9675-164X
Winnie Wan-Yee TsoDepartment of Paediatrics & Adolescent Medicine, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-5859-015X
Fenghua SunDepartment of Health and Physical Education, The Education University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-5251-4087
Lirong LuoDepartment of Special Education and Counselling, The Education University of Hong Kong, 10 Lo Ping Road, Hong Kong SAR, China.
Li-Chih WangDepartment of Special Education and Counselling, The Education University of Hong Kong, 10 Lo Ping Road, Hong Kong SAR, China.ORCID 0000-0002-4011-7305
Yen Na YumDepartment of Special Education and Counselling, The Education University of Hong Kong, 10 Lo Ping Road, Hong Kong SAR, China.ORCID 0000-0002-2165-6813
Guandong XuCentre for Learning, Teaching and Technology, The Education University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-4493-6663
Su LiState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.

Funding

Multi-disciplinary Research Capacity Building Scheme Grant of The Education University of Hong Kong 1-32-04A29
6 · The paper itself

Abstract

backgroundSpecific learning difficulties (SpLD), ADHD, and ASD are the most common neurodevelopmental disorders (NDDs) found in mainstream schools. In addition to formal NDD diagnoses, children may exhibit NDD symptoms without meeting full diagnostic criteria, and heterogeneities and commonalities are frequently observed regardless of whether children have been diagnosed or not, raising concerns about the lack of inclusive support for all. Following the transdiagnostic approach and biopsychosocial model, this study aims to cluster and profile children with these symptoms via cognitive, psychological, and ecological factors, using an unsupervised machine learning algorithm.

methodsBased on parent-report checklists, 267 Chinese primary school children in Grades 1–4 with at least one type of NDD symptoms were identified (164 boys; age in months: M = 102, SD = 17.30) from a bigger dataset (N = 1,034). A typically developing (TD) control group was created and matched with the NDD group in terms of age, gender, nonverbal IQ, and family socioeconomic status (SES). By using exploratory and confirmatory analyses, executive functioning, visual processing, and linguistic skills were extracted as cognitive factors, while internalising problems, externalising problems, positive child-parent relationships, and negative child-parent relationships were extracted as psychological and ecological factors.

resultsK-means clustering based on the seven extracted core factors identified five distinct clusters. Three clusters exhibited specific cognitive weaknesses, while the other two mainly showed psychosocial problems. Two severe-symptom groups (i.e., the Linguistic Difficulties group and the Psychosocial Difficulties group) also demonstrated worse academic and mental health outcomes.

conclusionsOur findings demonstrate the potential to focus on symptoms beyond diagnostic labels, as well as the inclusion of psychosocial factors alongside cognitive ones, thereby contributing to the design of more targeted and comprehensive support for children with special education needs and informing current inclusive education practice in China. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderSpecific Learning DisorderChildChinaClustering AlgorithmsEast Asian PeopleFemaleHumansMaleInclusive educationMachine learningNeurodevelopmental disordersSpecial education needs

Identifiers

PMID41486113
PMCPMC12870329

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.