Evidence map›Paper›PMID 41486075›Full record

ArticleThe journal of pathology. Clinical research2026

Prognostic significance of beta-adrenergic receptor expression in oesophageal adenocarcinoma.

Talita Oliveira, Swathi Sasi, James Trainor, Damian T McManus, Stephen McQuaid, Claire Lewis, Jacqueline A James, Helen G Coleman, Úna C McMenamin, Richard C Turkington

Abstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Talita OliveiraPatrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-8170-0989
Swathi SasiPatrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
James TrainorDepartment of Pathology, Belfast Health and Social Care Trust, Belfast, UK.
Damian T McManusDepartment of Pathology, Belfast Health and Social Care Trust, Belfast, UK.
Stephen McQuaidNorthern Ireland Biobank, The Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Claire LewisNorthern Ireland Biobank, The Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Jacqueline A JamesNorthern Ireland Biobank, The Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Helen G ColemanCentre for Public Health, Queen's University Belfast, Belfast, UK.
Úna C McMenaminCentre for Public Health, Queen's University Belfast, Belfast, UK.
Richard C TurkingtonCentre for Public Health, Queen's University Belfast, Belfast, UK.ORCID 0000-0003-3164-1890

Funding

Belfast Health and Social Care Trust Charitable FundsCancer Research UKCancer Research UK Career Establishment AwardHealth and Social Care Research and Development Division
6 · The paper itself

Abstract

Expression of the β-adrenergic receptors' family has been associated with survival outcomes in multiple different cancer types, showing their potential to act as prognostic factors. No previous work has evaluated these receptors in relation to survival in oesophageal adenocarcinoma. We sought to analyse the expression of β

Indexed as

AdenocarcinomaBiomarkers, TumorEsophageal NeoplasmsReceptors, Adrenergic, beta-1Receptors, Adrenergic, beta-2AdultAgedDisease-Free SurvivalFemaleHumansImmunohistochemistryKaplan-Meier EstimateMaleMiddle AgedNeoadjuvant TherapyPrognosisADRB1 protein, humanADRB2 protein, humanBiomarkers, TumorReceptors, Adrenergic, beta-1Receptors, Adrenergic, beta-2adenocarcinomabeta adrenergic receptorsimmunohistochemistryoesophageal cancertumour biomarker

Identifiers

PMID41486075
PMCPMC12765628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.