Evidence map›Paper›PMID 41485525›Full record

ArticleContemporary clinical trials2026

Testing the effects of a text message intervention on depression and distress among Latino dementia caregivers: A randomized controlled trial protocol.

Jaime Perales-Puchalt, Mariana Ramírez-Mantilla, Henry P Moore, Idaly Velez-Uribe, Vanessa Sepulveda-Rivera, Rachel Ruiz, Mónica Fracachán-Cabrera, Yesenia Herrera, Christina Baker, Antonio Miras-Neira and 9 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Jaime Perales-PuchaltUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: jperales@kumc.edu.
Mariana Ramírez-MantillaUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: mramirez3@kumc.edu.
Henry P MooreUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address: hmoore@med.miami.edu.
Idaly Velez-UribeWien Center for Alzheimer's Disease and Memory Disorders, Florida Alzheimer's Disease Research Center, Miami, FL, USA. Electronic address: idaly.velezuribe2@msmc.com.
Vanessa Sepulveda-RiveraUniversity of Puerto Rico, San Juan, PR 00936, USA. Electronic address: vanessa.sepulveda@upr.edu.
Rachel RuizUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: rruiz2@kumc.edu.
Mónica Fracachán-CabreraUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: mfracachancabrera@kumc.edu.
Yesenia HerreraUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: yherrera@kumc.edu.
Christina BakerUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: cbaker10@kumc.edu.
Antonio Miras-NeiraUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: amirasneira@kumc.edu.
Becky BothwellUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: rbothwell@kumc.edu.
Heidi AndersonUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: handerson8@kumc.edu.
Tina LewandowskiUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: tlewandowski@kumc.edu.
Francisco J DiazUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: fdiaz@kumc.edu.
K Allen GreinerUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: agreiner@kumc.edu.
Kristine WilliamsUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: kwilliams1@kumc.edu.
Eric D VidoniUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: evidoni@kumc.edu.
Edward EllerbeckUniversity of Kansas Medical Center, Kansas City, KS, USA. Electronic address: eellerbe@kumc.edu.
Jeffrey M BurnsUniversity of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA. Electronic address: 1jburns2@kumc.edu.

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mohammad Haeri · 2021 to 2026
$25.3M
SAFE Futures: Supporting American Indian and Alaska Native (AIAN) Maternal Health through Virtual Engagement and Community EmpowermentP20GM139733 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Christie Befort · 2023 to 2026
$11.5M
Testing the effects of a text message caregiver support intervention for LatinosR01AG082306 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jaime Perales Puchalt · 2024 to 2026
$2.3M
NIA NIH HHS P30 AG072973NIA NIH HHS R01 AG082306NIGMS NIH HHS P20 GM139733
6 · The paper itself

Abstract

backgroundLatino caregivers have poor mental health and access to caregiver support services. Here, we describe the protocol for a randomized controlled trial (RCT) to evaluate the effect of a text message intervention on depression and distress among informal Latino dementia caregivers. We will also assess mechanisms of action.

methodsWe are enrolling 288 Latino dementia informal caregivers 18 or older into a parallel group RCT. Participants randomized to the intervention group receive a remote, asynchronous, bilingual, bi-directional, 6-month texting program focused on dementia education, skill-building and community resources. The control group enters a 7-month waitlist after which they are offered the same intervention as the intervention group. Randomization is stratified by each of the four recruitment sites at a 1:1 ratio. Outcomes (e.g., caregiver depressive symptomatology, distress) are measured via surveys at baseline, 3, 6 and 7 months.

conclusionsThis RCT addresses two priority areas: eliminating dementia disparities and optimizing caregiver support. Findings have the potential to make clinical and policy-relevant contributions by providing appropriate caregiver support to Latinos in a highly scalable way. Protocol version/date: 1/14/2025.

Indexed as

CaregiversDementiaDepressionHispanic or LatinoPsychological DistressStress, PsychologicalText MessagingFemaleHumansMaleRandomized Controlled Trials as TopicSocial SupportWhiteCaregivingClinical trialDementiaLatinosmHealth

Identifiers

PMID41485525
PMCPMC12865795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.