ArticleEcology letters2026
Negative Frequency-Dependent Selection Promotes Strain Structure in a Plant Pathogen.
Article in Ecology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Negative Frequency-Dependent Selection Promotes Strain Structure in a Plant Pathogen.Ecology letters · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Specific recognition of microbial virulence factors (effectors) by host defence proteins can generate negative frequency-dependent selection (NFDS), enabling the maintenance of strain diversity. Our characterisation of 76 Midwestern US Pseudomonas syringae strains and 1104 global strains confirmed high strain diversity, but also revealed that strains are structured into similarity modules, consistent with core genome phylogeny but unexplained by host, location or genetic linkage. We developed a stochastic computational model that embraces the large variability now known to characterise effector repertoires. We show that NFDS can not only generate modular strain structure but is required to maintain modularity under genetic exchange, for which there is evidence in the data. These modules form through the emergence of groups of pathogens virulent to dominant hosts at a given time. Thus, eco-evolutionary dynamics contribute to strain coexistence through flux in the modules that represent niches within the host population.
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Registered trials
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