ReviewMolecular biotechnology2026
Beyond Tanacetum cinerariifolium: Advances in Pyrethrins Biosynthesis and Prospects for Engineered Cell Factories.
Review in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
Abstract
Pyrethrins are powerful natural insecticides traditionally extracted from the flowers of Tanacetum cinerariifolium. While effective and environmentally friendly, their agricultural production is limited by genetic variability, environmental factors, and labor-intensive cultivation. Advances in understanding the pyrethrin biosynthetic pathway, including the discovery and heterologous synthesis of key enzymes, have created new opportunities to rethink production methods. This review covers current knowledge of pyrethrin biosynthesis, focusing on precursor pathways and the challenges that hinder their heterologous production. We also discuss the remaining gaps and how synthetic biology and metabolic engineering can solve these issues. By shifting the focus from traditional flower farming to engineered cell factories, we suggest a new approach for achieving scalable, consistent, and sustainable pyrethrin production.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.