Evidence map›Paper›PMID 41485020›Full record

ArticleBMC geriatrics2026

Cross-sectional associations between physical activity and sarcopenia at different life stages: evidence from CHARLS.

Yongyu Huang, Qing Wang, Guangjie Wang, Ming Ding, Yanwei You, Fangbo Li, Taoran Wang, Yongtao Yan

Abstract read
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yongyu Huang *School of Physical Education and Sports Science, South China Normal University, Guangzhou, China.
Qing Wang *Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing, China.
Guangjie WangSchool of Physical Education and Sports Science, South China Normal University, Guangzhou, China.
Ming DingDepartment of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211,166, China.
Yanwei YouDivision of Sports Science & Physical Education, Tsinghua University, Beijing, China.
Fangbo LiSchool of Physical Education and Sports Science, South China Normal University, Guangzhou, China.
Taoran WangShenzhen Technology University, School of Physical Education and Art, Shenzhen, China. 32626735@qq.com.
Yongtao YanSchool of Physical Education, Shenzhen Polytechnic University, Shenzhen, China. sunbird@szpu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia, defined as progressive loss of skeletal muscle mass and function, is a major health issue with economic consequences in aging societies. Physical activity is recognized as preventive, but its long-term impact across different life stages is not well established. This study examined the association between lifetime physical activity and sarcopenia prevalence using nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS).

methodsData from the 2014 CHARLS Life History Survey were matched with 2015 cross-sectional health assessments. After excluding participants younger than 60 years or with missing data, a final sample of 6,696 individuals was analyzed. Physical activity at different life stages was assessed using a self-reported questionnaire in the 2014 Life History Survey. Sarcopenia was classified according to the AWGS 2019 criteria. Multivariate logistic regression was conducted to evaluate the association between physical activity at different life stages and sarcopenia prevalence. A significance level of 0.05 was adopted for hypothesis testing.

resultsAmong the study participants, 51.7% were without sarcopenia, 36.0% had possible sarcopenia, and 12.3% had sarcopenia. Across all life stages, individuals with sarcopenia were less likely to have engaged in regular physical activity. After adjusting for all covariates, engaging in physical activity for at least one year at any life stage was associated with a 47% lower odds of sarcopenia (OR = 0.53, 95% CI: 0.40-0.69). The strongest protective effect was observed for physical activity during middle adulthood (41-65 years) (OR = 0.36, 95% CI: 0.19-0.69), whereas physical activity in young adulthood (≤ 40 years) and older adulthood (> 65 years) showed no significant associations.

conclusionOur findings highlight that maintaining physical activity, particularly during middle adulthood, is associated with reduced risk of sarcopenia. Because physical activity was self-reported, future research should employ objective measures and longitudinal designs to confirm these associations.

Indexed as

ExerciseSarcopeniaAgedChinaCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceSelf ReportAgingLife course perspectivePhysical activitySarcopenia

Identifiers

PMID41485020
PMCPMC12866481

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.