ArticleApplied biochemistry and biotechnology2026
Green Synthesis and Characterization of Copper Nanoparticles Using Cinnamon (Cinnamomum Zeylanicum L.) Extract with Evaluation of Cytotoxicity Activities.
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Abstract
Green synthesis is a method in which metal nanoparticles (MNPs) are produced by using biological synthesizing agents, including plant extracts. Copper nanoparticles (CuNPs) are used in a wide range of biological and non-biological sciences due to their unique physical and chemical properties. The research aim is to investigate the potential of producing CuNPs with cinnamon plant extract. Synthesis of CuNPs was done with the hydroalcoholic extract of the cinnamon plant. The Tyndall effect, ultraviolet-visible (UV-Vis), dynamic light Scattering (DLS), fourier transform infrared spectroscopy (FTIR), zeta potential (Zeta-P), raman spectroscopy, field emission scanning electron microscopy (FE-SEM), atomic force microscope (AFM), and x-ray diffraction (XRD) were used for evaluating CuNPs. Cytotoxic effects of nanoparticles (NPs) were measured. The average size of CuNPs is 40 nm and spherical, homogeneous, with uniform particle size. The highest cytotoxicity of NPs occurred after 48 h. Green synthesis of NPs using edible and medicinal plants such as cinnamon i.e. a suitable option due to its low cost, environmental friendliness, and easy process. In this research, the results indicate that the synthesized CuNPs have strong cytotoxic effects.
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