ArticleBMC surgery2026
Residual lung volume changes after thoracoscopic lobectomy and segmentectomy based on 3D-CT: a retrospective preliminary validation study.
Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThree-dimensional CT enables quantitative assessment of lobar and lung volumes after anatomical resection, yet how postoperative compensation pattern relates to operation type remains unclear.
methodsIn this single-center retrospective cohort (n = 124), preoperative and postoperative 3D-CT volumes were quantified. The primary outcome was postoperative change in lung volume relative to preoperative baseline (Vpost - Vpre, %). Multivariable models adjusted for age, sex, BMI, and smoking; p values were FDR-adjusted. We also compared measured versus predicted percentages derived from preoperative ipsilateral lung and target-lobe volumes.
resultsOverall, postoperative total lung volume decreased modestly, with larger ipsilateral loss than contralateral change. After adjustment, left-lower lobe resections showed a greater ipsilateral volume decrease after lobectomy than after segmentectomy (FDR-significant), whereas differences in other lobes were small or uncertain after multiplicity control. Measured versus predicted comparisons indicated partial compensation on the operated side and near-preservation on the contralateral side.
conclusionsFindings highlight side-dependent compensation patterns and suggest that operation choice may influence ipsilateral volume loss in selected settings. Given the retrospective design and small surgical subgroups, these results are hypothesis-generating and warrant prospective validation and integration with oncologic considerations.
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