Evidence map›Paper›PMID 41484646›Full record

ArticleBiological research2026

INO80 regulates promoter-associated R-loops to coordinate transcription and maintain genome stability in embryonic stem cells.

Hoseong Lim, Ohbeom Kwon, Hyeonwoo La, Hyeonji Lee, Heeji Lee, Jeong-Tae Do, Hyuk Song, Youngsok Choi, Kwonho Hong

Erratum issuedAbstract read
In one paragraph

Article in Biological research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hoseong Lim *Department of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Ohbeom Kwon *Department of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Hyeonwoo LaDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Hyeonji LeeDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Heeji LeeDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Jeong-Tae DoDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Hyuk SongDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Youngsok ChoiDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea.
Kwonho HongDepartment of Stem Cell and Regenerative Biotechnology and Institute of Advanced Regenerative Science, Konkuk University, Seoul, 05029, Korea. hongk@konkuk.ac.kr.ORCID http://orcid.org/0000-0001-7479-4091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisCell cycle regulationChromatin remodelingEmbryonic stem cellsGenome stabilityHydroxyureaINO80R-loop homeostasisTranscription-replication conflict

Identifiers

PMID41484646
PMCPMC12865974

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.