ArticleItalian journal of pediatrics2026
Clinical features and analysis of the misdiagnosis of anomalous origin of the left coronary artery from the pulmonary artery in children.
Article in Italian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- A retrospective analysis of initial ultrasonographic misdiagnosis of fibrous hamartoma of infancy at the ultrasound center of a tertiary hospital in China.Frontiers in pediatrics · 2026Article
- Anomalous origin of the left coronary artery from the pulmonary artery with coronary artery fistula in an adult presenting with cardiomegaly, abnormal electrocardiogram, myocardial perfusion defect and pulmonary hypertension: a case report.Frontiers in cardiovascular medicine · 2026Article
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Abstract
backgroundAnomalous left coronary artery from the pulmonary artery(ALCAPA) is a rare congenital cardiovascular malformation. The main manifestations are non-specific and prone to misdiagnose. Without active treatment, the prognosis is poor. The study summarized the clinical characteristics of ALCAPA in children, analyzed the causes of misdiagnosis, and aimed to improve the rate of accurate initial diagnosis.
methodsWe retrospectively analyzed 19 children diagnosed with ALCAPA at the Children’s Hospital of Chongqing Medical University between December 2012 and July 2022. Diagnosed was established by color Doppler echocardiography, digital subtraction angiography(DSA), or confirmed intraoperatively. Patients were categorized into infant(≤ 1 year) and child(> 1 year) groups. Clinical characteristics, and causes of misdiagnosis were summarized and analyzed.
resultsFourteen of the 19 patients(73.68%) were misdiagnosed at their initial echocardiographic examination. The correct diagnosis was subsequently confirmed through repeat echocardiography or DSA. Clinical features differed between infant and child groups.
conclusionElectrocardiogram can provide valuable diagnostic clues for ALCAPA. Echocardiography remains a primary diagnostic tool, but it is also the most frequent source of misdiagnosis. Comprehensively evaluation combining clinical manifestations with multiple auxiliary examinations is essential to reduce misdiagnosis errors and improve the accuracy of first-time diagnosis.
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