Evidence map›Paper›PMID 41484535›Full record

ArticleVirus genes2026

Molecular identification and Genogrouping of chicken infectious anaemia virus from commercial layer flocks of Gujarat, India.

Bhavesh R Pandor, Harshad C Chauhan, Kishan K Sharma, Sandip S Patel, Arun C Patel, Rohit S Parmar, Sushil K Mohapatra, Harsh A Patel, Akash K Thakore

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Article in Virus genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bhavesh R PandorVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Harshad C ChauhanVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Kishan K SharmaVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India. kishan12sharma@kamdhenuuni.edu.in.
Sandip S PatelVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Arun C PatelVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Rohit S ParmarVeterinary Pathology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Sushil K MohapatraAnimal Biotechnology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Harsh A PatelVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.
Akash K ThakoreVeterinary Microbiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Sardarkrushinagar, Banaskantha, Gujarat, 385005, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to ascertain the positive incidence, genogrouping, and amino acid variations in the VP1 gene of chicken infectious anaemia virus (CIAV) among layer flocks in Gujarat, India. A single pooled sample was collected from each of the 32 farms visited, all of which had a history and post-mortem lesions suggestive of chicken infectious anaemia (CIA) across five districts of the state. Samples were processed, and CIAV was confirmed by PCR targeting the VP3 gene and genogrouped. In histopathological examination, generalised lymphoid atrophy with prominent lymphocyte depletion was observed in both the cortex and medulla of the thymus and bursa of Fabricius. Out of the total 32 pooled tissue samples, 21 (65.63%) tested positive for the presence of CIAV. The effect of vaccination on disease prevention was found to be nonsignificant, as all five vaccinated flocks (100%) tested positive. Upon phylogenetic analysis, these isolates were found to be virulent and of genogroup IIIb (sub-clade G-II-b of clade G-II), but distant to strains of genogroup IIIa and II. The notable amino acid difference of C149M/E was similar to the change reported from South India in 2022. Amino acids were different from IIIa strains at V75I, L125I, K139Q, S287A, and G370S positions, Cux-1 vaccine at V157M, S287T, and G370S, and group I strains at L125I positions. The possession of virulence-determining amino acids, variations from vaccine strains and IIIa field strains, and divergence from other Indian strains might be the cause of escape from vaccinal immunity.

Indexed as

Chicken anemia virusCircoviridae InfectionsPoultry DiseasesAnimalsCapsid ProteinsChickensGenotypeIndiaPhylogenyCapsid ProteinsVP1 protein, Chicken anemia virusChicken infectious anaemia virus (CIAV)GenogroupingGenome sequencingPolymerase chain reaction (PCR)VaccineVP1 gene

Identifiers

PMID41484535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.