ArticleIndian journal of pediatrics2026
Congenital Anomalies of Kidney and Urinary Tract in Children - Clinical Spectrum and Complications.
Article in Indian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Comparative analysis of kidney growth and function in children with different types of unilateral congenital renal anomalies: a 2 year follow-up study.International urology and nephrology · 2026Article
- Clinical and Molecular characteristics of kidney and urinary tract congenital anomalies in a cohort of Egyptian patients using whole-exome sequencing.Molecular biology reports · 2026Article
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4 authors.
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Abstract
objectivesTo study the spectrum of congenital anomalies of the kidney and urinary tract (CAKUT), and to examine the clinical presentation and potential complications.
methodsA total of 304 children were recruited (216 retrospectively and 88 prospectively). Clinical data were obtained from records in the retrospective cases, while clinical assessments, laboratory tests, and imaging were conducted as needed in the prospective cases.
resultsPrimary vesicoureteric reflux (VUR) was the most common cause of CAKUT (34.2%), followed by posterior urethral valve (PUV) at 24% and pelvi-ureteric junction obstruction (PUJO) at 13.1%. Antenatal detection was the most common mode of identification (47.6%), followed by detection after urinary tract infection (UTI) in 29.5% of cases. Extrarenal manifestations occurred in 6.5% of cases. Recurrent UTI was the most common complication, seen in 42.3%. Additionally, 11.5% had hypertension, and 10% had a glomerular filtration rate (GFR) of less than 60 ml/min/1.73 m
conclusionsPrimary VUR is the most common CAKUT, and the antenatal detection of anomalies is crucial. The prevalence of chronic kidney disease (CKD) stage 2 and above is quite high among CAKUT, particularly PUV, renal hypodysplasia, and VUR, warranting close nephrology follow-up.
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