Evidence map›Paper›PMID 41484511›Full record

ReviewProbiotics and antimicrobial proteins2026

The Biofilm Plight in Healthcare: Orchestration and Control by Lactiplantibacillus plantarum.

Sharleen Livina Isaac, Adelene Ai-Lian Song, Wan Nur Ismah Wan Ahmad Kamil

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sharleen Livina IsaacDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, 43400, Malaysia.
Adelene Ai-Lian SongDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, 43400, Malaysia.
Wan Nur Ismah Wan Ahmad KamilDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, 43400, Malaysia. wn_ismah@upm.edu.my.

Funding

Universiti Putra Malaysia GP-IPM/2021/9695400
6 · The paper itself

Abstract

The clinical consequences of biofilm-related infections are on the rise. Biofilm-related infections represent a mounting burden on healthcare worldwide, posing a significant challenge to patient care and health infrastructure. Another notorious function that needs to be underlined is the association of biofilms with medical devices. Considering the fact that bacteria under biofilm make them virulent and resistant to antibiotics, targeting the biofilms is a crucial area of investigation. Therefore, alternative approaches that extend beyond conventional antibiotic therapies are necessary to overcome biofilm-related infections. In this regard, Lactiplantibacillus plantarum, a probiotic bacterium, has lately shown promising outcomes as an antibiofilm agent. Largely renowned for its antimicrobial metabolite production, L. plantarum could be a potential alternative to improve biofilm-related treatment and its cost associated with biofilm infections. Therefore, the present review aims to provide a comprehensive understanding and implications of L. plantarum as an antibiofilm agent regardless of its biological form against pathogens in healthcare. Additionally, the potential of L. plantarum as a biofilm producer and its engineered applications in clinical applications and therapeutic use will also be discussed in this review.

Indexed as

BiofilmsLactiplantibacillus plantarumProbioticsAnti-Bacterial AgentsAntibiosisHumansAnti-Bacterial AgentsAntibiofilmAntimicrobial resistanceBiofilmLactiplantibacillus plantarumPostbiotic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.