Evidence map›Paper›PMID 41484510›Full record

ArticleClinical journal of gastroenterology2026

Successful preoperative diagnosis and laparoscopic endoscopic cooperative surgery for gastric plexiform fibromyxoma: a case report.

Takeru Yoshimoto, Shusuke Yagi, Naoki Akazawa, Hideki Miyazaki, Naoki Enomoto, Kyoko Nohara, Chizu Yokoi, Toru Igari, Kazuhiko Yamada, Norihiro Kokudo

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In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Takeru YoshimotoDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Shusuke YagiDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Naoki AkazawaDepartment of Gastroenterology, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Hideki MiyazakiDepartment of Pathology, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Naoki EnomotoDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Kyoko NoharaDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Chizu YokoiDepartment of Gastroenterology, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Toru IgariDepartment of Pathology, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.
Kazuhiko YamadaDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan. kayamada@hosp.ncgm.go.jp.ORCID http://orcid.org/0000-0002-7234-4844
Norihiro KokudoDepartment of Surgery, Center Hospital of the National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plexiform fibromyxoma (PF) is a rare gastric submucosal tumor that presents diagnostic challenges due to its nonspecific clinical and imaging findings. Preoperative diagnosis is difficult, and optimal management remains unclear. We report the successful diagnosis and resection of PF using laparoscopic endoscopic cooperative surgery (LECS), a minimally invasive approach that preserves gastric function. An 81-year-old woman with a known gastric submucosal tumor was referred after endoscopy showed tumor enlargement and central depression. Endoscopic ultrasound revealed a hypoechoic mass originating from the second layer of the gastric wall. Bite-on-bite biopsies of the delle identified spindle cells embedded in a mucinous stroma. Immunohistochemistry showed positivity for alpha-smooth muscle actin and negativity for c-KIT, CD34, S100, and desmin, confirming PF. Given the increase in size, central depression, and associated anemia, surgical resection was indicated. The patient underwent LECS, which allowed for complete resection with minimal margins and preservation of gastric anatomy. The procedure was uneventful, and recovery was smooth. Histopathological findings confirmed the diagnosis of PF. This is the first reported case of PF resected by planned LECS following preoperative diagnosis by bite-on-bite biopsy. LECS offers a safe and effective option for managing PF and other submucosal tumors in anatomically sensitive locations.

Indexed as

FibromaGastroscopyLaparoscopyStomach NeoplasmsAged, 80 and overEndosonographyFemaleHumansGastrectomyGastric submucosal tumorGastrointestinal stromal tumorLaparoscopic endoscopic cooperative surgeryPlexiform fibromyxoma

Identifiers

PMID41484510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.