Evidence map›Paper›PMID 41484498›Full record

Observational studyDigestive diseases and sciences2026

Long-Term Outcomes and Rebleeding Risk Factors in Suspected Small Bowel Bleeding: A Study Based on the Modified Saurin Classification.

Sachiyo Onishi, Kiichi Otani, Naoya Masuda, Hiroki Taniguchi, Kentaro Kojima, Jun Takada, Masaya Kubota, Takashi Ibuka, Masahito Shimizu

Abstract readObservational Study
In one paragraph

Observational study in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sachiyo OnishiGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan. gogo_nishi0924@yahoo.co.jp.
Kiichi OtaniGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Naoya MasudaGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Hiroki TaniguchiGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Kentaro KojimaGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Jun TakadaGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Masaya KubotaGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Takashi IbukaGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.
Masahito ShimizuGifu University School of Medicine Graduate School of Medicine, Endoscopy, 1-1 Yanagido, Gifu City, 501-1193, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall-bowel endoscopy is essential for diagnosing and managing suspected small bowel bleeding (SSBB); however, rebleeding after treatment remains clinically challenging. Although several rebleeding prediction models have been proposed, few are based on endoscopic findings, and data on long-term outcomes are limited.

aimsThis study aimed to evaluate rebleeding risk factors and long-term outcomes using the modified Saurin classification (modified SC), which is compatible with balloon-assisted endoscopy (BAE).

methodsWe retrospectively evaluated 278 consecutive patients with OGIB who underwent capsule endoscopy (CE) or BAE between October 2008 and December 2023. The lesions were categorized using modified SC as P0 (n = 58), P1 (n = 109), P2 (n = 71), or no findings (n = 40). Treatment was classified as endoscopic or definitive (surgical or interventional radiology).

resultsOf the 278 patients (mean age 67.7 years; 150 males), 158 had occult OGIB and 120 had overt OGIB. Treatment was administered to 73 patients (46 endoscopic and 27 definitive cases). Over a mean follow-up of 2.2 years, 32 patients (11.5%) experienced rebleeding. Multivariate analysis identified modified SC P1 lesions (odds ratios [ORs], 2.33; p = 0.03), antiplatelet drugs use (ORs 3.02, p = 0.04) and treatment interventions (ORs, 2.28; p = 0.02) as independent predictors. The 3-year rebleeding rate was higher in P1 (27.2%) than in P0 (9.5%) and P2 (13.8%). Rebleeding was more frequent in the endoscopic group (39.9%) than in the definitive group (10.5%; p = 0.04).

conclusionModified SC P1 lesions were significantly associated with rebleeding. Proactive treatment strategies and long-term follow-up are crucial for effective management of SSBB.

Indexed as

Capsule EndoscopyGastrointestinal HemorrhageIntestinal DiseasesIntestine, SmallSingle-Balloon EnteroscopyAgedFemaleFollow-Up StudiesHumansMaleOccult BloodPredictive Value of TestsRecurrenceRetrospective StudiesRisk FactorsTime FactorsBalloon-assisted endoscopyCapsule endoscopyModified Saurin classificationObscure gastrointestinal bleeding (OGIB)Suspected small bowel bleeding (SSBB)

Identifiers

PMID41484498
PMCPMC13357490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.