Evidence map›Paper›PMID 41484407›Full record

ArticleScientific reports2026

Neurological symptoms and physical exam findings 6-11 months post-COVID-19: a cohort study.

Bruno Fukelmann Guedes, Ana Paula Ritto, Andre Macedo Serafim Silva, Antonio Edvan Camelo Filho, Cristiane de Araújo Martins Moreno, Marcos Vinícius Oliveira Marques, Mariana Ribeiro Marcondes da Silveira, Raphael de Luca eTuma, José Pedro Soares Baima, Sâmia Yasin Wayhs and 11 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Bruno Fukelmann GuedesDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. bruno.guedes@hc.fm.usp.br.ORCID http://orcid.org/0000-0001-8391-2117
Ana Paula RittoDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7509-0528
Andre Macedo Serafim SilvaDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-5792-5878
Antonio Edvan Camelo FilhoDivision of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, CE, Brazil.ORCID http://orcid.org/0000-0002-1213-1687
Cristiane de Araújo Martins MorenoDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-5867-6359
Marcos Vinícius Oliveira MarquesSaint Louis University Hospital, St Louis, USA.ORCID http://orcid.org/0000-0002-3084-0620
Mariana Ribeiro Marcondes da SilveiraDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1611-2325
Raphael de Luca eTumaDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-2100-5869
José Pedro Soares BaimaDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-2708-1181
Sâmia Yasin WayhsDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-3299-8760
Rodrigo de Holanda MendonçaDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7520-3353
Cristiana Borges PereiraDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-8417-1699
Bruno Diógenes IepsenDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-6828-9600
Barbara Leite CostaDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4550-2720
Emanuelle Roberta da Silva AquinoDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6178-5831
Julia Chartouni RodriguesDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-8121-7572
Geraldo Busatto FilhoDepartment of Psychiatry, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-4749-4602
Edmar ZanoteliDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4991-6760
Suely Kazue Nagahashi MarieDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-4419-7928
Ricardo NitriniDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-5721-1525
Luiz Henrique Martins CastroDepartment of Neurology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1878-8548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatic neurological complications are an underexplored component of post-acute sequelae of SARS-CoV-2 infection. We evaluated long-term somatic neurological symptoms, examination findings, and suspected diagnoses among adults hospitalized for COVID-19. A total of 708 survivors were assessed 6–11 months after discharge using a structured three-step neurological evaluation based on the World Health Organization Protocol for Epidemiologic Studies of Neurologic Disorders: an adapted symptom questionnaire, a brief standardized neurological examination, and a full neurological consult. Muscle weakness, gait impairment, and paresthesias remained the most frequent symptoms at follow-up. Longer hospital stay predicted all three symptoms, and diabetes was associated with both gait impairment and paresthesias. Common examination findings included monoparesis, hemiparesis, and gradient-pattern sensory loss. Clinically suspected diagnoses included neuromuscular disease in 26%, cerebrovascular disease in 10%, and epilepsy in only 2.7% of cases. Logistic regression linked neuromuscular disease to paresthesias and tandem-walk failure, cerebrovascular disease to facial paralysis, and epilepsy to loss-of-contact episodes. A simplified screening model derived through best-subsets selection identified five informative items from the WHO protocol: paresthesias, facial paralysis, tandem walk, index–nose test, and loss-of-contact episodes. These findings indicate that somatic neurological abnormalities remain frequent months after severe COVID-19 and that a brief bedside subset may support efficient post-COVID neurological triage.

Indexed as

COVID-19Nervous System DiseasesAdultCohort StudiesFemaleHumansMaleMiddle AgedNeurologic ExaminationNeuromuscular DiseasesPhysical ExaminationPost-Acute COVID-19 SyndromeSARS-CoV-2Neurologic manifestationsNeuromuscular diseasesPeripheral nervous system diseasesPost-Acute COVID-19 syndrome

Identifiers

PMID41484407
PMCPMC12852936

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.