ArticleNPJ digital medicine2026
Differential privacy for medical deep learning: methods, tradeoffs, and deployment implications.
Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safeguarding biomedical AI: a critical scoping review of privacy-enhancing technologies, hybrid approaches, and deployment models.Frontiers in digital health · 2026Pooled it
- From Integrated Care to Learning Systems.Healthcare (Basel, Switzerland) · 2026Review
- Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- "Doing no harm" in the digital age: navigating tradeoffs and operational considerations for privacy-preserving deep learning in medicine.NPJ digital medicine · 2026Article
- Considering the missing science of retraining and maintenance in medical artificial intelligence, using ophthalmology as an exemplar.NPJ digital medicine · 2026Review
- The ethics of data mining in healthcare: challenges, frameworks, and future directions.BioData mining · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differential privacy (DP) is a prominent technique for protecting sensitive patient data in medical deep learning (DL), yet deploying it without compromising clinical utility or equity remains challenging. This scoping review synthesizes applications of DP in medical DL across centralized and federated settings. A structured search identified 74 eligible studies published through March 2025. Across modalities and tasks, DP, especially via DP-SGD, can maintain clinically acceptable performance under moderate privacy budgets (ϵ ≈ 10), particularly in imaging. However, strict privacy (ϵ ≈ 1) often leads to substantial accuracy loss, with amplified degradation in smaller or heterogeneous datasets. Only a minority of studies evaluate fairness, and several report that DP can widen subgroup performance gaps. Beyond DP-SGD, alternative mechanisms, including generative modeling, local DP, and hybrid federated designs, are emerging, but reporting of privacy parameters remains inconsistent. We identify key gaps in fairness auditing and standardization, and outline priorities for equitable, clinically robust privacy-preserving DL.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.