ReviewCommunications biology2026
Reshaping cancer cell plasticity by P-body dynamics and protein translation.
Review in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A P-body-related risk score predicts prognosis and immune microenvironment in lung adenocarcinoma.Translational cancer research · 2026Article
- The Art of Domesticating Proteins: How Cancer Cells Adapt to Therapeutic and Environmental Stressors.International journal of molecular sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Processing bodies (P-bodies) are membrane-less organelles composed of condensed mRNAs and proteins that play essential role in mRNAs decay and storage, contributing to the translational control of cellular proteostasis. Regulation of P-body assembly/disassembly by signaling events, cellular stress or specific environmental conditions shapes the rate of RNA turnover and protein synthesis, controlling cell growth, differentiation and survival. Deregulation of protein translation is an important factor for tumor development and progression and cancer cells benefit from P-bodies to reshape their proteome to support specific metabolic needs and promote tumor development, progression and metastasis. Hence, understanding the composition and the regulation of P-bodies, both under physiological and pathological conditions, will define the mechanisms underlying cancer cell plasticity and develop novel therapeutic strategies to inhibit cancer growth and metastasis. Here, we will discuss the principal mechanisms of P-body regulation and function, with special focus on the role of these ribonucleoprotein condensates in cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.