Evidence map›Paper›PMID 41484162›Full record

ReviewNPJ Parkinson's disease2026

Consensus expert recommendations for referral of Parkinson's disease patients for deep brain stimulation surgery.

Delaram Safarpour, Meredith Spindler, Travis H Turner, Neepa Patel, Okeanis Vaou, Laura Y Cabrera, Christopher Tolleson, Philip W Tipton, Camila Aquino, Todd M Herrington and 24 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Psychiatric consultation outcomes in deep brain stimulation candidacy: clinical and psychosocial correlates from a retrospective cohort.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Delaram SafarpourDepartment of Neurology, Oregon Health and Science University, Portland, OR, USA. safarpou@ohsu.edu.
Meredith SpindlerDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Travis H TurnerDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.
Neepa PatelDepartment of Neurology, Rush University Medical Center, Chicago, IL, USA.
Okeanis VaouDepartment of Neurology, University of Texas, San Antonio, TX, USA.
Laura Y CabreraDepartment of Engineering Science and Mechanics, Center for Neural Engineering, The Pennsylvania State University, University Park, PA, USA.
Christopher TollesonDepartment of Neurology, The Cole Center for Parkinson's and Movement Disorders, The University of Tennessee Medical Center, Knoxville, TN, USA.
Philip W TiptonDepartment of Neurology, The Cole Center for Parkinson's and Movement Disorders, The University of Tennessee Medical Center, Knoxville, TN, USA.
Camila AquinoDepartment of Clinical Neurosciences, Hotchkiss Brin Institute, University of Calgary, Calgary, AB, Canada.
Todd M HerringtonDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Christos SidiropoulosDepartment of Neurology and Ophthalmology, Michigan State University, East Lansing, MI, USA.
Nathan HantkeDepartment of Neurology, Oregon Health and Science University, Portland, OR, USA.
Mitesh LotiaDepartment of Neurology, Advent Health Research Institute, Orlando, FL, USA.
Svjetlana MiocinovicDepartment of Neurology, Emory Healthcare, Atlanta, GA, USA.
Vibhash D SharmaDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Kelly A MillsDepartment of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA.
Kathryn Wyman-ChickStruthers Parkinson's Center, HealthPartners Park Nicollet, Golden Valley, MN, USA.
Camilla KilbaneDepartment of Neurology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Corneliu LucaDepartment of Neurology, University of Miami Health System, Miami, FL, USA.
Leonardo AlmeidaDepartment of Neurology, University of Minnesota, Minneapolis, MN, USA.
Joshua RosenowDepartment of Neurosurgery, Feinberg School of Medicine of Northwestern University, Chicago, IL, USA.
Hwai Yin OoiParkinson's Disease and Movement Disorders Institute, Department of Neurology, Weill Cornell Medicine, New York, NY, USA.
Zoltan MariDepartment of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Lan LuoDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Renato P MunhozEdmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, ON, Canada.
Sol De JesusDepartment of Neurology, Penn State Health, Hershey, PA, USA.
Harini SarvaParkinson's Disease and Movement Disorders Institute, Department of Neurology, Weill Cornell Medicine, New York, NY, USA.
Monica ArenaDepartment of Neurology, Oregon Health and Science University, Portland, OR, USA.
Gonzalo RevueltaDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.
Kelvin L ChouDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Alfonso FasanoEdmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, ON, Canada.
Mustafa S SiddiquiDepartment of Neurology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Joohi Jimenez-ShahedDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Functional Neurosurgical working group of the Parkinson Study Group

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KEVIN M DUFF, Lisa C Silbert · 2020 to 2026
$28.6M
NIA NIH HHS P30 AG066518
6 · The paper itself

Abstract

Deep brain Stimulation (DBS) surgery effectively alleviates troublesome motor symptoms of Parkinson's disease (PD) such as tremor, rigidity, bradykinesia, motor fluctuations and dyskinesia. It also improves some non-motor symptoms and quality of life. DBS should thus be considered when these symptoms interfere with quality of life despite optimal medical treatment. While DBS benefits are clear, access by eligible patients remains low. Patients and their caregivers should be educated regarding DBS surgery and referrals for surgical evaluation should occur alongside ongoing medication adjustments-particularly when those changes fail to adequately control motor symptoms-regardless of the stage of disease progression. This international panel of DBS experts developed consensus recommendations with the goals of promoting timely referrals and approvals, while reducing misconceptions and stigma associated with brain surgery. These recommendations provide a framework for referring providers, ensuring that appropriate candidates receive timely access to this beneficial treatment.

Identifiers

PMID41484162
PMCPMC12848073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.