ArticlePharmaceutical biology2026
Exploring techniques for extraction of silver fir (
Article in Pharmaceutical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Assessment of Liver and Kidney Safety of Silver Fir (Food science & nutrition · 2026Article
- Sample Preparation and Separation of Lignans by Liquid Chromatography.Journal of separation science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextSilver fir (
objectiveTo compare extraction techniques and identify the optimal method for obtaining high-quality silver fir extracts with strong antioxidant activity and minimal cytotoxicity. MATERIALS &
methodsExtracts from bark and branches were prepared using subcritical water extraction (SWE, 70-200 °C), supercritical CO
resultsThe SWE bark extract at 100 °C (SWE-BA-100) showed the highest TPC (73.8 mg GAE/g), lignan content (secoisolariciresinol 204.7 µg/mL), and antioxidant activity (DPPH: 24.2, ABTS: 32.0 mg GAE/g). Bark extracts had superior bioactive profiles compared to branches, though branch extractions gave higher yields. All extracts were non-cytotoxic. SWE-BA-100 inhibited cell migration, indicating a complex interaction between composition and cellular response. DISCUSSION AND
conclusionSWE at 100 °C is a promising green method for producing potent antioxidant extracts from
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Registered trials
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