Evidence map›Paper›PMID 41483474›Full record

ArticleInorganic chemistry2026

Optimizing Intracellular Transport of Antimicrobial Metallohelices Delivers Selective Nanomolar Potency in

Miles L Postings, Nicola J Rogers, Georgia Shreeve, Hualong Song, Guy Clarkson, Anish Mistry, John Moat, Grace Taylor-Joyce, Nicholas R Waterfield, Peter Scott

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inorganic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miles L PostingsDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, U.K.ORCID 0000-0003-4933-3052
Nicola J RogersDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Kowloon 999077, Hong Kong.ORCID 0000-0002-9604-5136
Georgia ShreeveDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, U.K.
Hualong SongBeijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Centre of Endogenous Prophylactic of Ministry of Education of China, Capital Medical University, Beijing 100069, China.
Guy ClarksonDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, U.K.
Anish MistryDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, U.K.
John MoatSchool of Life Sciences, University of Warwick, Gibbet Hill Campus, Coventry CV4 7AL, U.K.
Grace Taylor-JoyceWarwick Medical School, University of Warwick, Gibbet Hill Campus, Coventry CV4 7AL, U.K.
Nicholas R WaterfieldWarwick Medical School, University of Warwick, Gibbet Hill Campus, Coventry CV4 7AL, U.K.
Peter ScottDepartment of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, U.K.ORCID 0000-0002-5656-7060

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate large discrepancies in antimicrobial potency between cationic amphipathic metallohelix architectures, 22 new optically pure candidates were synthesized via self-assembly. A total of 34 compounds were tested against

Indexed as

Anti-Bacterial AgentsEscherichia coliMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial Agents

Identifiers

PMID41483474
PMCPMC12820927

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.