ArticleAntonie van Leeuwenhoek2026
The antagonistic coevolution between Pseudomonas sivasensis W-6 and the cold-adapted phage VW6S.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
Coevolution is a widespread phenomenon, especially prominent in the dynamic interactions between bacteria and bacteriophages. The continuous antagonistic coevolution, characterized by cycles of bacterial resistance and phage infectivity, drives the diversification of phage adsorption structures and bacterial surface receptors, with significant ecological and evolutionary implications. This study investigated the short-term coevolution (40 days) between Pseudomonas sivasensis W-6 and its cold-adapted phage VW6S, isolated from the Napahai plateau wetland. Genomic resequencing revealed reciprocal adaptations, with mutations occurring in bacterial resistance genes and phage infection-related genes. We identified a putative receptor-binding mechanism wherein the phage-encoded tail fiber protein (gp28) specifically interacts with bacterial surface receptors, mediating host recognition and adsorption. Furthermore, variations in a prophage region during coevolution were found to influence phage adsorption efficiency, indicating that prophage-driven evolutionary changes can affect bacterial survival strategies beyond direct virus-host interactions.
Indexed as
Identifiers
41483357What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.