Evidence map›Paper›PMID 41483319›Full record

ArticleMikrochimica acta2026

Colorimetric and luminescent detection of cysteamine based on lanthanide-doped upconversion nanoparticles and gold nanoparticles.

Leilei Sun, Haoran Chen, Zixuan Fang, Wenxin Deng, You-Gan Wang, Congbin Fan

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leilei SunJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, P. R. China. sunleilei216@163.com.
Haoran ChenJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, P. R. China.
Zixuan FangJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, P. R. China.
Wenxin DengJiangxi Chemical Industry Advanced Technical School, Nanchang, 330006, P. R. China.
You-Gan WangJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, P. R. China. ygwang0214@163.com.
Congbin FanJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, P. R. China. congbinfan@163.com.

Funding

Jiangxi Provincial Career Early Young Science and Technology Talent Cultivation Special Fund Project 20244BCE52246Jiangxi Provincial Key Laboratory of Organic Functional Molecules 2024SSY05141National Natural Science Foundation of China 22261020Ph.D. start-up funds of Jiangxi Science and Technology Normal University 2024BSQD52Ph.D. start-up funds of Jiangxi Science and Technology Normal University 2024BSQD67
6 · The paper itself

Abstract

A colorimetric/luminescent detection nanoprobe based on polyacrylic acid (PAA)-modified lanthanide-doped upconversion nanoparticles (PAA-UCNPs) and gold nanoparticles (AuNPs) is prepared for cysteamine detection. PAA-UCNPs (NaYF4:Yb,Er@NaYF4) exhibit green and red emission under near-infrared laser excitation. In the presence of cysteamine, citrate-stabilized AuNPs aggregate, causing a significant red shift in their absorption peak and weakening the red luminescence of PAA-UCNPs based on the inner filter effect (IFE). This nanoprobe enables rapid (5 min) and precise determination of cysteamine, with a wide linear range (0.1–1.0 µM in colorimetric mode and 0.25–1.25 µM in luminescence mode) and a low detection limit (44.4 nM in colorimetric mode and 23.3 nM in luminescence mode). Moreover, this dual-mode method is used for cysteamine detection in calf serum, demonstrating high sensitivity and reproducibility.

Indexed as

Cysteamine detectionDual-mode detectionGold nanoparticlesInner filter effectLanthanide-doped nanoparticles

Identifiers

PMID41483319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.