Evidence map›Paper›PMID 41483231›Full record

ArticleMikrochimica acta2026

Porphyrin micro-nano assemblies for capture and isolation of extracellular vesicles.

Yilong Xing, Shengnan Liu, Xiangshan Yang, Juan Li, Rui Zhang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yilong Xing *NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Chang Chun, 130021, China.
Shengnan Liu *China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Xiangshan YangNHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Chang Chun, 130021, China.
Juan LiNHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Chang Chun, 130021, China. li_juan@jlu.edu.cn.
Rui ZhangNHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Chang Chun, 130021, China. zhangrui625827@jlu.edu.cn.

Funding

Natural Science Foundation of Jilin Province 20220101193JC
6 · The paper itself

Abstract

Polyethyleneimine (PEI) modified 5,10,15,20-tetrakis(4-(hydroxyl)phenyl)porphyrin (THPP) assemblies with different morphologies are prepared via an evaporation-induced self-assembly method. The obtained THPP/PEI assemblies have positive surface potentials under physiological conditions. Therefore, THPP/PEI assemblies can capture extracellular vesicles (EVs) from MCF-7 cells via electrostatic interaction. Furthermore, THPP/PEI assemblies can also isolate EVs in size according to their different morphologies. The EV capture efficiency of THPP/PEI assembly is much high than those of inorganic ZnO-based nanowire arrays, although both rely on electrostatic attraction to capture EVs. Using the THPP/PEI assemblies, we demonstrated that the expression level of CD147 of EVs derived from the urine samples of colon cancer patients was 4.3-fold higher than that from the urine samples of healthy donors with a p-value less than 0.01. It is expected that the new THPP/PEI assemblies in this work has potential to be applied to liquid biopsy technology because of their portability and cost effectiveness.

Indexed as

Extracellular VesiclesPorphyrinsColonic NeoplasmsHumansMCF-7 CellsNanowiresPolyethyleneiminePolyethyleneiminePorphyrinsCancer cellExtracellular vesiclesMicro-nano assembliesPorphyrinSelf-assembly

Identifiers

PMID41483231

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.