Evidence map›Paper›PMID 41483192›Full record

SynthesisArchives of women's mental health2026

Global prevalence and associated factors of severe fear of childbirth: a systematic review and Meta-Analysis.

Mahsa Maghalian, Zohreh Alizadeh-Dibazari, Mojgan Mirghafourvand

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Archives of women's mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Mahsa MaghalianStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.
Zohreh Alizadeh-DibazariDepartment of Midwifery, TaMS.C., Islamic Azad University, Tabriz, Islamic Republic of Iran.
Mojgan MirghafourvandSocial Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran. mirghafourvand@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFear of childbirth (FoC), particularly its severe form (tokophobia), is a significant public health concern associated with adverse maternal and neonatal outcomes. While previous meta-analyses have provided global prevalence estimates, significant knowledge gaps remain due to limited studies. This study aimed to provide an updated global prevalence estimate of severe FoC and explore sources of heterogeneity and associated risk factors.

methodsA systematic review and meta-analysis was conducted following PRISMA and MOOSE guidelines. We searched international and Persian databases from inception until June 2025 for cross-sectional and cohort studies reporting severe FoC prevalence in pregnant women using validated tools with defined cutoffs. Two reviewers independently performed data extraction and quality assessment using the Newcastle-Ottawa Scale. Random-effects models were used for meta-analysis, with heterogeneity assessed via I² statistic. Subgroup analyses and meta-regressions explored variation sources. Risk factors were synthesized descriptively, though nulliparity and unplanned pregnancy allowed meta-analysis.

resultsFrom 67 included studies (n = 905,504 participants), the pooled prevalence of severe FoC was 16.5% (95% CI: 13.8-19.5%), with significant heterogeneity (I² = 99.45%). Assessment tools and cutoffs were major heterogeneity sources (p < 0.001), with prevalence ranging from 3.7% to 58.7%. Country of study was also a significant moderator (p < 0.001). Meta-regression showed no significant association with maternal age, gestational age, nulliparity percentage, or publication year. Key risk factors included previous traumatic birth, anxiety/depression symptoms, and inadequate social support. Nulliparous women had higher odds of severe FoC (OR = 1.36, 95% CI: 1.04-1.76), as did those with unplanned pregnancy (OR = 1.85, 95% CI: 1.29-2.65).

conclusionSevere FoC affects approximately one in six women globally. The substantial heterogeneity, largely due to methodological variations, underscores the need for standardized assessment protocols. Identified associations with factors such as previous traumatic birth and anxiety highlight the condition's multifactorial nature, emphasizing the importance of targeted screening and evidence-based interventions aligned with Sustainable Development Goal (SDG) 3 to improve maternal mental health.

Indexed as

FearParturitionPhobic DisordersPregnant PeopleAdultCross-Sectional StudiesFemaleGlobal HealthHumansPregnancyPrevalenceRisk FactorsMeta-AnalysisParturitionPrevalenceRisk factorsTokophobia

Identifiers

PMID41483192

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.