Evidence map›Paper›PMID 41483182›Full record

ArticleMicrobial ecology2026

Structure and Diversity of the Microbiome in Amazonian Sand Flies: Insights into Vector-Microbe Interactions.

Katerine Caviedes-Triana, Rafael Vivero-Gómez, Daniela Duque-Granda, Howard Junca, Gloria Cadavid-Restrepo, Claudia X Moreno-Herrera

Abstract read
In one paragraph

Article in Microbial ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katerine Caviedes-TrianaGrupo de Microbiodiversidad y Bioprospección, Faculty of Sciences, Universidad Nacional de Colombia, Street 59 A # 63-20, Medellín, 050003, Colombia.
Rafael Vivero-GómezGrupo de Microbiodiversidad y Bioprospección, Faculty of Sciences, Universidad Nacional de Colombia, Street 59 A # 63-20, Medellín, 050003, Colombia.
Daniela Duque-GrandaGrupo de Microbiodiversidad y Bioprospección, Faculty of Sciences, Universidad Nacional de Colombia, Street 59 A # 63-20, Medellín, 050003, Colombia.
Howard JuncaRG Microbial Ecology: Metabolism, Genomics & Evolution, Div. Ecogenomics & Holobionts, Microbiomas Foundation, LT11A, Chia, 250008, Colombia.
Gloria Cadavid-RestrepoGrupo de Microbiodiversidad y Bioprospección, Faculty of Sciences, Universidad Nacional de Colombia, Street 59 A # 63-20, Medellín, 050003, Colombia.
Claudia X Moreno-HerreraGrupo de Microbiodiversidad y Bioprospección, Faculty of Sciences, Universidad Nacional de Colombia, Street 59 A # 63-20, Medellín, 050003, Colombia. cxmoreno@unal.edu.co.

Funding

Ministerio de Ciencia, Tecnología e Innovación Scholarship Program of Ministerio de Ciencia, Tecnología e Innovación, Call 15, for Human Capital Development in the context of the Bicentennial and the 2021-2022 Biennial Plan.Universidad Nacional de Colombia Hermes 57545
6 · The paper itself

Abstract

This study uses high-throughput sequencing of the 16S rRNA gene and specific PCR to analyze the microbiome and identify secondary endosymbionts in sand flies from the Amazon region, important vectors of parasitic and viral diseases. Specimens of Psychodopygus, Trichophoromyia, Nyssomyia, Trichopygomyia and Brumptomyia were collected and analyzed. The results revealed that the richness, diversity, and composition of the microbiome are influenced by several factors, such as insect species specific composition, and insect sex. The core microbiome community was represented by 18 genera, with Novosphingobium, Cutibacterium, Methylobacterium and Staphylococcus being the most prevalent. The highest diversity at the genus level was observed in sand flies of epidemiological relevance as Psychodopygus and Nyssomyia, dominated by Novosphingobium (66.5%), Cutibacterium (29.4%) and Methylobacterium (20.4%), while in non-vectors such as Trichophoromyia, Delftia predominated (59.9%). Endosymbiont analysis showed a high prevalence of Cardinium (20%) and Wolbachia (33%), as well as the presence of Spiroplasma, Arsenophonus and Rickettsia. In addition, some bacterial genera related to the inhibition of parasite development, which have entomopathogenic activity and are involved in the degradation of insecticides were identified. Our results are relevant and contribute to the knowledge of the characterization of the microbiome and the endosymbionts in leishmaniasis vectors in the Amazon region and show promise for improving vector management, highlighting the importance of investigating their interaction with pathogens and their impact on vector biology.

Indexed as

BacteriaInsect VectorsMicrobiotaPsychodidaeAnimalsBiodiversityBrazilDNA, BacterialFemaleMalePhylogenyRNA, Ribosomal, 16SSymbiosisDNA, BacterialRNA, Ribosomal, 16SAmazonCaquetáDiversityEndosymbiontMicrobiotaVectors

Identifiers

PMID41483182
PMCPMC12827397

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.