ReviewPain and therapy2026
Research Progress on Radiofrequency Treatment of Primary Trigeminal Neuralgia in the V2 Maxillary Nerve.
Review in Pain and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary trigeminal neuralgia (TN) involving the V2 maxillary nerve presents unique therapeutic challenges. Traditional radiofrequency techniques at the semilunar ganglion often lack selectivity and carry risks of injuring adjacent nerves. The recently refined CT-guided foramen ovale puncture radiofrequency thermocoagulation technique has significantly improved outcomes for V2 TN. This narrative review systematically explores the evolution of radiofrequency treatment for V2 TN, with a particular focus on comparing the efficacy and safety of different puncture pathways. We emphasize the superior clinical utility of the infrazygomatic approach, which offers greater precision and fewer complications than the obsolete orbital and mandibular routes. Furthermore, we discuss the impact of technical innovations, such as personalized needle modification, on treatment precision. This review aims to consolidate current evidence and provide practical, evidence-based guidance for clinicians managing this complex pain condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.