Evidence map›Paper›PMID 41483039›Full record

ArticleMikrochimica acta2026

Accurate neuron-specific enolase quantification via amino acid analysis-IDMS: enabling magnetic nanoparticle-based immunochromatography development.

Yalin Hu, Jihao Si, Zhanwei Liang, Hua Ye, Jie Xie, Lei Guo, Xiaoqing Li, Tao Peng, Xinhua Dai

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yalin Hu *Center for Advanced Measurement Science, Mass Spectrometry Engineering Technology Research Center, National Institute of Metrology, Beijing, 100029, China.
Jihao Si *Center for Advanced Measurement Science, Mass Spectrometry Engineering Technology Research Center, National Institute of Metrology, Beijing, 100029, China.
Zhanwei LiangCenter for Advanced Measurement Science, Mass Spectrometry Engineering Technology Research Center, National Institute of Metrology, Beijing, 100029, China.
Hua YeThe Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University/ The Third Affiliated Hospital of Shanghai University / Wenzhou People's Hospital, Wenzhou, Zhejiang, 325000, China.
Jie XieCenter for Advanced Measurement Science, Mass Spectrometry Engineering Technology Research Center, National Institute of Metrology, Beijing, 100029, China.
Lei GuoDepartment of Anesthesiology, Critical Care and Pain Medicine, The Second Affliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Xiaoqing LiThe Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University/ The Third Affiliated Hospital of Shanghai University / Wenzhou People's Hospital, Wenzhou, Zhejiang, 325000, China. wzslixq@163.com.
Tao PengCenter for Advanced Measurement Science, Mass Spectrometry Engineering Technology Research Center, National Institute of Metrology, Beijing, 100029, China. pengtao@nim.ac.cn.
Xinhua DaiChina National Institute of Standardization, Beijing, 100191, China. daixh@nim.ac.cn.

Funding

Central Public-Interest Scientific Institution Basal Research Fund, National Institute of Metrology AKYRC2305National Key Research and Development Program of China 2022YFF0608402Plan for Leading Talents of Science and Technology Innovation WR2202Science and technology project of the State Administration for Market Regulation 2023MK182
6 · The paper itself

Abstract

An accurate method is presented for quantifying recombinant neuron-specific enolase (NSE) using isotope dilution liquid chromatography-mass spectrometry (IDMS) based on amino acid analysis. Traceable to the International System of Units - moles, the NSE concentration was determined as (0.0924 ± 0.0074) mg∙mL

Indexed as

Amino AcidsChromatography, AffinityMagnetite NanoparticlesPhosphopyruvate HydrataseChromatography, LiquidHumansLimit of DetectionMass SpectrometryReproducibility of ResultsAmino AcidsMagnetite NanoparticlesPhosphopyruvate HydrataseImmunochromatographic assayMetrological traceabilityPoint-of-care detection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.