Evidence map›Paper›PMID 41482746›Full record

ArticleJournal of oral rehabilitation2026

Effects of a Standardised Medical-Dental Collaborative Protocol on Acute Stroke Rehabilitation: A Multicentre Prospective Cohort Study.

Yu Yoshizumi, Yoshiyuki Sasaki, Motoki Inaji, Jun Karakama, Ayako Nakane, Chiaki Matsubara, Junichi Furuya, Shinsuke Irie, Shinichi Wakabayashi, Masateru Katayama and 13 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Yu YoshizumiDepartment of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0006-8070-2062
Yoshiyuki SasakiClinical Dental Research Promotion Unit, Faculty of Dentistry, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-5400-3958
Motoki InajiDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Jun KarakamaDepartment of Neurosurgery, Ome Medical Center, Tokyo, Japan.
Ayako NakaneDepartment of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Chiaki MatsubaraDepartment of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Junichi FuruyaDepartment of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8018-4537
Shinsuke IrieDepartment of Neurosurgery, Kushiro Kojinkai Memorial Hospital, Hokkaido, Japan.
Shinichi WakabayashiDepartment of Neurosurgery, Suiseikai Kajikawa Hospital, Hiroshima, Japan.
Masateru KatayamaDepartment of Neurosurgery, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Katsuhiko SakaiDepartment of Oral Medicine and Hospital Dentistry, Tokyo Dental College, Chiba, Japan.
Takanori HayakawaDepartment of Neurosurgery, National Hospital Organization Disaster Medical Center, Tokyo, Japan.
Yoshihisa KawanoDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Nobuhiro InokuchiDepartment of Gerodontology and Dysphagia Rehabilitation, JA Toride Medical Center, Ibaraki, Japan.
Manabu IshiharaEmergency and Critical Care Medicine, Tokushima University Hospital, Tokushima, Japan.
Hideyuki TakanoDepartment of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculty of Dentistry, Tokushima, Japan.
Nobukazu KomoribayashiIwate Prefectural Advanced Critical Care and Emergency Center, Iwate Medical University, Iwate, Japan.
Yasushi TamadaGerodontology, Department of Oral Health Science, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan.
George UmemotoSwallowing Disorders Center, Fukuoka University Hospital, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-8458-1329
Kazuyuki MatsunagaDepartment of Neurology, Brain Attack Center Ota Memorial Hospital, Hiroshima, Japan.
Junichi YamazoeSection of Geriatric Dentistry and Perioperative Medicine in Dentistry, Kyushu University Hospital, Fukuoka, Japan.
Haruka ToharaDepartment of Dysphagia Rehabilitation, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-5514-6419
Taketoshi MaeharaDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Funding

Japan Agency for Medical Research and Development 16768752.H28-30
6 · The paper itself

Abstract

backgroundAcute stroke often causes complications such as aspiration pneumonia, which can be prevented through oral hygiene. However, evidence supporting individualised oral care remains limited. We developed a multidisciplinary oral function management protocol and evaluated its benefits in patients with acute stroke, including its impact on aspiration pneumonia.

methodsIn this prospective multicentre cohort study, data from 1616 patients with acute stroke admitted to participating hospitals between 31 July 2017, and 27 January 2021 were analysed. Hospitals implemented our oral function management program (Protocol group) or provided conventional oral care (control group). To minimise confounding by baseline severity, propensity scores were estimated using stroke severity and initial complications; patients were matched 1:1 using nearest-neighbour matching with a calliper of 0.2, resulting in 313 matched pairs (n = 626). Primary outcome was the incidence of aspiration pneumonia; secondary outcomes were hospital stay length and oral function improvement.

resultsNo significant differences in aspiration pneumonia onset rates were detected between the protocol and control groups (p = 0.7639). Compared to controls, the protocol group showed significant improvements in oral hygiene (p < 0.0001), tongue mobility (p = 0.0292), and FOIS scores (p = 0.0005). Time from admission to discharge evaluation (p < 0.0001) and total length of hospital stay (p = 0.0018) were significantly reduced. Compared to administration of conventional oral care, implementation of this Protocol facilitated earlier oral management and feeding/swallowing rehabilitation, potentially reducing hospital stays and enhancing oral functions.

conclusionThe protocol may enhance oral functionality and reduce hospitalisation duration by systematising multidisciplinary oral management and swallowing rehabilitation, alongside supporting conventional pneumonia prevention strategies.

Indexed as

Oral HygienePneumonia, AspirationStrokeStroke RehabilitationAgedAged, 80 and overClinical ProtocolsFemaleHumansLength of StayMaleMiddle AgedProspective Studiesaspiration pneumoniadeglutitionmulticentre studypropensity scoreprospective studiesstroke

Identifiers

PMID41482746
PMCPMC12980049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.