ArticleG3 (Bethesda, Md.)2026
Identification of regulatory candidate genes for Lentinula edodes pileus development based on transcriptome analysis.
Article in G3 (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Environmentally Associated Developmental Reprogramming from Mycelial Growth to Fruiting Body Formation inJournal of fungi (Basel, Switzerland) · 2026Article
- Comparative transcriptomics reveals stage-specific regulatory pathways of ear thickening in Auricularia polytricha.PloS one · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The pileus serves as a primary determinant of market grade and commercial value in Lentinula edodes. To elucidate the molecular mechanisms governing pileus development, we conducted comparative transcriptome analysis via RNA sequencing across 3 distinct developmental stages: Early button stage, Young fruiting body stage, and mature fruiting body stage. Gene expression profiling revealed a substantial number of differentially expressed genes (DEGs) between stages, with 283 conserved DEGs spanning the entire developmental continuum. Systematic mining of these conserved DEGs identified 3 candidate regulatory genes encoding: Alpha-amylase, Heat shock protein 70 (HSP70), Phosphatidylserine decarboxylase. Quantitative PCR validation confirmed the accuracy of both RNA-Seq data and DEG identification. Enzymatic activity assays demonstrated significant stage-specific variations in: Antioxidant enzyme activities, Membrane lipid peroxidation levels. This study provides valuable insights into the molecular framework underlying pileus morphogenesis in Lentinula edodes.
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