Evidence map›Paper›PMID 41482365›Full record

ReviewIn vivo (Athens, Greece)

Medical Cannabis for Best Supportive Care of Patients Affected by Cancers of the Head and Neck: A Narrative Review.

Francesco Perri, Maria Luisa Marciano, Alessia Zotta, Monica Pontone, Arianna Piccirillo, Marina Casale, Pasquale DI Filippo, Maria Rosaria Sarno, Roberta D' Aniello, Marco Cascella and 1 more

Abstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco PerriHead and Neck Oncology Unit, Istituto Nazionale Tumori di Napoli IRCCS "G. Pascale", Naples, Italy.
Maria Luisa MarcianoHead and Neck Oncology Unit, Istituto Nazionale Tumori di Napoli IRCCS "G. Pascale", Naples, Italy; ml.marciano@istitutotumori.na.it.
Alessia ZottaMedical Oncology, Department of Precision Medicine, degli Studi della Campania Luigi Vanvitelli, Naples, Italy.
Monica PontoneHead and Neck Oncology Unit, Istituto Nazionale Tumori di Napoli IRCCS "G. Pascale", Naples, Italy.
Arianna PiccirilloHead and Neck Oncology Unit, Istituto Nazionale Tumori di Napoli IRCCS "G. Pascale", Naples, Italy.
Marina CasalePharmacy, Istituto Nazionale Tumori di Napoli - IRCCS "G. Pascale", Naples, Italy.
Pasquale DI FilippoPharmacy, Istituto Nazionale Tumori di Napoli - IRCCS "G. Pascale", Naples, Italy.
Maria Rosaria SarnoPharmacy, Istituto Nazionale Tumori di Napoli - IRCCS "G. Pascale", Naples, Italy.
Roberta D' AnielloPharmacy, Istituto Nazionale Tumori di Napoli - IRCCS "G. Pascale", Naples, Italy.
Marco Cascella *Anesthesiology and Pain Therapy Unit, Università degli Studi di Salerno, Salerno, Italy.
Piera Maiolino *Pharmacy, Istituto Nazionale Tumori di Napoli - IRCCS "G. Pascale", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancers of the head and neck, including malignancies of the oral cavity, pharynx, larynx, and salivary glands, are often associated with severe symptoms that negatively impact quality of life. Patients commonly experience pain, nausea, cachexia (severe weight loss), dysphagia (difficulty swallowing), and xerostomia (dry mouth), all of which can be exacerbated by both the disease and its treatments, such as surgery, radiation, and chemotherapy. Research has demonstrated that medical cannabis can be effective in managing symptoms such as chronic pain, nausea, vomiting, and anxiety, making it a valuable option in cancer care. Its ability to interact with the endocannabinoid system to reduce nociception (pain perception) and inflammation makes it particularly suitable for the complex symptom burden of patients with head and neck cancer. This review explores the role of the endocannabinoid system and medical cannabis in mitigating symptoms and improving patient outcomes, as well as its place within the comprehensive care of patients with cancers of the head and neck.

Indexed as

Head and Neck NeoplasmsMedical MarijuanaEndocannabinoidsHumansQuality of LifeEndocannabinoidsMedical MarijuanacannabidiolcannabisDelta-9-tetrahydrocannabinolhead and neck cancerreviewsupportive care

Identifiers

PMID41482365
PMCPMC12764220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.