Evidence map›Paper›PMID 41481751›Full record

ArticlePLoS neglected tropical diseases2026

Onchocerciasis and non-communicable diseases in the Bafut Health District, Cameroon: Knowledge, attitudes, and practices towards community-directed treatment with ivermectin.

Irene U Ajonina-Ekoti, Promise A Aghaeze, Joan Ebanga, Theophilus A Ekoti, Tiburce Gangue, Beri A Gariba, Moses A Mbanwi, Adolph A Fozao, Carine K Nfor, Mbunkah D Achukwi and 1 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irene U Ajonina-EkotiDepartment of Microbiology and Parasitology, The University of Bamenda, Bambili, Cameroon.
Promise A AghaezeDepartment of Microbiology and Parasitology, The University of Bamenda, Bambili, Cameroon.
Joan EbangaDepartment of Microbiology and Parasitology, The University of Bamenda, Bambili, Cameroon.
Theophilus A EkotiMcGadi Education and Research Initiative, Buea, Cameroon.
Tiburce GangueDepartment of Zoology, The University of Bamenda, Bambili, Cameroon.
Beri A GaribaNorthwest Regional Delegation of Public Health, Bamenda, Cameroon.
Moses A MbanwiDistrict Health Service, Bafut, Cameroon.
Adolph A FozaoDistrict Health Service, Bafut, Cameroon.
Carine K NforMcGadi Education and Research Initiative, Buea, Cameroon.
Mbunkah D AchukwiTOZARD Laboratory, Bambili, Cameroon.
Marcelus U AjoninaMcGadi Education and Research Initiative, Buea, Cameroon.ORCID https://orcid.org/0000-0003-0847-9928

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnchocerciasis remains a public health problem in Cameroon despite years of community-directed treatment with ivermectin (CDTI). Its persistence increasingly overlaps with the rising burden of non-communicable diseases (NCDs). Community knowledge, attitudes, and practices (KAP) toward onchocerciasis and CDTI, as well as the coexistence of chronic NCDs, may influence the success of elimination programs. METHODOLOGY: A community-based cross-sectional study was conducted between April and June 2022 in Bafut Health District, Northwest Cameroon. Using a structured, interviewer-administered questionnaire, information was collected on sociodemographic characteristics, knowledge, attitudes, and practices related to onchocerciasis and CDTI, as well as symptoms and comorbidities associated with NCDs. Descriptive statistics were used to summarize responses, while the association between quantitative variables was determined using the Chi-square test and logistic regression analysis. Statistical significance was set at p < 0.05.

resultsOf the 250 respondents (mean age 40.9 ± 13.6 years), 96.8% had heard of onchocerciasis, though only 46.0% correctly identified the filarial worm as the cause. Good knowledge, a positive attitude, and good practices regarding onchocerciasis and CDTI were observed in 78.0%, 61.3%, and 90.4% of the respondents, respectively. Symptoms of onchocerciasis were reported by 188 participants (75.2%), with itching being the most common (50.4%). Of these, 46 (24.5%) also reported a diagnosis of NCD, while 84 (44.7%) reported a family history of NCDs. Arthritis (32.4%) was the most common self-reported NCD, and hypertension (14.0%) was the most frequent family history.

conclusionsThis study revealed high levels of knowledge and good practices regarding onchocerciasis and CDTI; however, knowledge gaps and concerns about side effects continue to hinder the uptake of ivermectin. The coexistence of onchocerciasis with chronic NCDs highlights the need for integrated disease management and reinforced health education to support elimination goals.

Indexed as

Antiparasitic AgentsHealth Knowledge, Attitudes, PracticeIvermectinNoncommunicable DiseasesOnchocerciasisAdolescentAdultAgedCameroonCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAntiparasitic AgentsIvermectin

Identifiers

PMID41481751
PMCPMC12782443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.