Evidence map›Paper›PMID 41481743›Full record

ArticleScience advances2026

A softness zwitterionic micelles efficiently deliver inhaled nintedanib by enhancing airway mucus penetration.

Binghua Wang, Peibo Fan, Fanqi Guo, Zhihui Song, Zhenzhong Zhang, Xiang Lu, Jinjin Shi

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Binghua WangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-9345-7568
Peibo FanSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Fanqi GuoSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhihui SongSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhenzhong ZhangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0009-0004-8430-7989
Xiang LuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-6166-9881
Jinjin ShiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0003-1531-7265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhalation therapy shows great potential for treating idiopathic pulmonary fibrosis (IPF), but airway mucus imposes strong adhesive and steric barriers to drug delivery. Compared with other types of micelles, our results demonstrated that amphiphilic micelles formed by DSPE-PCB [carboxybetaine polymer conjugated to 1,2-distearoyl-

Indexed as

Drug CarriersIdiopathic Pulmonary FibrosisIndolesRespiratory MucosaAdministration, InhalationAnimalsAzo CompoundsBronchoalveolar LavageBronchoalveolar Lavage FluidDisease Models, AnimalFemaleLungMiceMice, Inbred C57BLMicellesPermeability1,2-distearoylphosphatidylethanolamineazobenzeneAzo CompoundsDrug CarriersIndolesMicellesnintedanibPhosphatidylethanolaminesProtein Kinase InhibitorsSurface-Active Agents

Identifiers

PMID41481743
PMCPMC12758532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.