Transition-metal-free electrochemical cross-electrophile coupling of activated benzyl alcohols and primary alkyl bromides.

Guang Chen, Changhao Huang, Like Luo, Dayu Tian, Xiaocheng Wang, Hai-Jun Zhang

Abstract read

In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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5 · Who and what money

Authors and funding

6 authors.

Guang ChenState Key Laboratory of Precision and Intelligent Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.ORCID 0009-0001-6794-8651

Changhao HuangState Key Laboratory of Precision and Intelligent Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.

Like LuoState Key Laboratory of Precision and Intelligent Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.

Dayu TianState Key Laboratory of Precision and Intelligent Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.

Xiaocheng WangDepartment of Rheumatology and Immunology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei, Anhui 230022, China.ORCID 0000-0002-5268-1050

Hai-Jun ZhangState Key Laboratory of Precision and Intelligent Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.ORCID 0000-0002-2963-0378

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross-electrophile coupling (XEC) has emerged as a powerful strategy for constructing carbon─carbon bonds. Here, we report the first transition-metal-free electrochemical XEC between readily available benzyl alcohol derivatives and primary alkyl bromides, enabling the efficient construction of C(sp

Identifiers

PMID41481718

DOI10.1126/sciadv.aeb3720

PMCPMC13162218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.