Evidence map›Paper›PMID 41481558›Full record

ArticlePloS one2026

Impaired estimated glomerular filtration rate and associated factors among adult patients living with HIV at Asella Referral and Teaching Hospital, Ethiopia: A cross-sectional study.

Tamiru Adugna Dadi, Teshome Tola Bedada, Abdurke Dido Akako, Legesse Tadesse Wodajo, Sebona Girma Moges, Wubshet Abraham Alemu

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Tamiru Adugna DadiDepartment of Internal Medicine, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.ORCID https://orcid.org/0009-0001-6586-8084
Teshome Tola BedadaDepartment of Internal Medicine, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.
Abdurke Dido AkakoDepartment of Internal Medicine, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.ORCID https://orcid.org/0009-0000-0358-4441
Legesse Tadesse WodajoDepartment of Public Health, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.
Sebona Girma MogesDepartment of Internal Medicine, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.ORCID https://orcid.org/0009-0008-3358-3624
Wubshet Abraham AlemuDepartment of Internal Medicine, College of Health Sciences, Arsi University, Asella, Oromia, Ethiopia.ORCID https://orcid.org/0009-0005-0134-8935

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Immunodeficiency Virus (HIV) remains a major global health challenge, particularly in sub-Saharan Africa. It is a multisystem disorder with significant renal involvement. In Ethiopia, limited data exist on the prevalence of impaired estimated glomerular filtration rate among patients with Human Immunodeficiency Virus. Identifying associated factors is critical for implementing targeted interventions to preserve renal function.

methodsAn institution-based cross-sectional study was conducted among 252 adult patients living with Human Immunodeficiency Virus from October 1 to December 30, 2024 at Asella Referral and Teaching Hospital. Data were collected via structured questionnaires and medical record reviews. Bivariate and multivariate logistic regression analyses were performed to identify factors associated with impaired glomerular filtration rate (estimated glomerular filtration rate <60 mL/min/1.73m2).

resultThe prevalence of impaired glomerular filtration rate was 18.7% (95% CI: 14.0-23.0). Factors significantly associated with impaired glomerular filtration rate included age > 40 years (AOR = 3.26; 95%CI: 1.17-9.12), history of smoking (AOR = 4.68; 95% CI: 1.87-11.70), opportunistic infections (AOR = 5.93; 95% CI: 2.23-15.74), diabetes mellitus (AOR = 3.86; 95% CI: 1.47-10.12) and hypertension (AOR = 2.71; CI: 1.07-6.82).

conclusionThe study found that around 19% of the studied population had impaired glomerular filtration rate. Targeted screening for kidney disease should focus on individuals older than 40years, smokers and those with opportunistic infections, diabetes mellitus or hypertension.

Indexed as

Glomerular Filtration RateHIV InfectionsAdultCross-Sectional StudiesEthiopiaFemaleHospitals, TeachingHumansMaleMiddle AgedPrevalenceReferral and ConsultationRisk FactorsYoung Adult

Identifiers

PMID41481558
PMCPMC12758773

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