Evidence map›Paper›PMID 41481288›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2026

Single-cell transcriptomics reveal alveolar macrophage-specific responses in single-hit ozone exposure model in mice.

Thao Vo, Ishita Choudhary, Sonika Patial, Yogesh Saini

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Thao VoDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States.
Ishita ChoudharyDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States.
Sonika PatialDivision of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, North Carolina, United States.
Yogesh SainiDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States.ORCID 0000-0002-8324-2122

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
Understanding the role of myeloid cells in ozone-induced airway diseaseR01ES030125 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2019 to 2024
$2.7M
Targeting Type-2 mucoinflammatory axis during the resolution of allergic lung inflammationR01ES035439 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Yogesh Saini · 2024 to 2026
$1.7M
Pathogenesis of mucous cell metaplasia in ozone-exposed airwaysR21ES034509 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SAINI, YOGESH · 2023 to 2024
$403k
HHS | NIH | National Institute of Environmental Health Sciences (DEHS) R01ES030125HHS | NIH | National Institute of Environmental Health Sciences (DEHS) R01ES035439HHS | NIH | National Institute of Environmental Health Sciences (DEHS) R21ES034509NCI NIH HHS P30 CA016086NIDDK NIH HHS P30 DK034987NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P30 ES025128NIEHS NIH HHS R01 ES030125NIEHS NIH HHS R01 ES035439NIEHS NIH HHS R21 ES034509
6 · The paper itself

Abstract

Alveolar macrophages (AMs), a highly plastic immune cell population, are among the first responders to inhaled ozone (O

Indexed as

Macrophages, AlveolarOzoneSingle-Cell AnalysisTranscriptomeAnimalsLungMaleMiceMice, Inbred C57BLOzonealveolar macrophageslung inflammationmiceozonescRNA-seq

Identifiers

PMID41481288
PMCPMC13623050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.