Evidence map›Paper›PMID 41481198›Full record

ArticleAnalytical chemistry2026

GNPS Feature-Based Molecular Networking as a Tool to Visualize Metabolic Toxicity from Drug-Drug Interactions: A Case Study with Methamphetamine and Ethanol.

Mingyu Kim, Ju-Hyun Kim, Seung Jin Yoo, Sooyeun Lee

Abstract read
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingyu KimCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu 42601, Republic of Korea.ORCID 0000-0001-7571-9456
Ju-Hyun KimCollege of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Republic of Korea.ORCID 0000-0002-6555-9716
Seung Jin YooKorean National Police University, 100-50, Hwangsan-gil, Sinchang-myeon, Asan-si, Chungcheongnam-do 31539, Republic of Korea.
Sooyeun LeeCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu 42601, Republic of Korea.ORCID 0000-0002-7649-0910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feature-Based Molecular Networking (FBMN) on the Global Natural Products Social Molecular Networking (GNPS) platform offers a transformative framework for visualizing drug-drug interaction (DDI)-driven metabolic reprogramming that conventional analytical approaches fail to capture. Here, we demonstrate its application as a novel strategy to resolve complex metabolic alterations arising from DDI-induced toxicity. Using FBMN-integrated MS

Indexed as

EthanolMethamphetamineAnimalsChromatography, LiquidDrug InteractionsEthanolMethamphetamine

Identifiers

PMID41481198
PMCPMC12809649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.