Evidence map›Paper›PMID 41481031›Full record

ArticleACS nano2026

Albumin Nanoparticles Co-Loaded with Dual Drugs for Enhanced Ferroptosis-Based Cancer Therapy through Modulating Cholesterol Metabolism.

Di Han, Binbin Ding, Pan Zheng, Jia Tan, Qi Meng, Wenying Zhang, Hao Chen, Ping'an Ma, Jun Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Di HanKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Binbin DingKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.ORCID 0000-0002-3717-857X
Pan ZhengKey Laboratory of Superlight Materials & Surface Technology of Ministry of Education, College of Material Sciences and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
Jia TanKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Qi MengKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.ORCID 0000-0003-1579-3819
Wenying ZhangKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Hao ChenKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Ping'an MaKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.ORCID 0000-0003-4198-5240
Jun LinKey Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.ORCID 0000-0001-9572-2134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a form of regulated cell death driven by lipid peroxidation, in which the diffusion of lipid peroxidation substrates on the plasma membrane is hindered by lipid rafts, thereby inhibiting the ferroptosis process. Lipid rafts are microdomains composed of cholesterol, sphingolipids, and specific proteins. Notably, cholesterol acyltransferase sterol

Indexed as

Antineoplastic AgentsAuranofinCholesterolFerroptosisNanoparticlesNeoplasmsSerum Albumin, HumanAnimalsCell Line, TumorHumansMiceSterol O-AcyltransferaseAntineoplastic AgentsAuranofinCholesterolSerum Albumin, HumanSterol O-Acyltransferasealbumin nanoparticlecholesterol metabolismferroptosisimmune activationlipid raft

Identifiers

PMID41481031
PMCPMC12825383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.