Evidence map›Paper›PMID 41480725›Full record

ArticlePest management science2026

From fertilizer to insecticide: urban leaf litter chemistry alters the survival landscape of Aedes aegypti.

Ana Luiza Caldatto, Gilberto Dinis Cozzer, Heloise Restello Remus, Raquel de Brito, Monica Santin Zanatta Schindler, Cássia Alves Lima-Rezende, Jacir Dal Magro, Renan de Souza Rezende

Abstract read
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana Luiza CaldattoCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0009-0006-2624-5809
Gilberto Dinis CozzerCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0003-4825-6032
Heloise Restello RemusCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0009-0007-0377-3681
Raquel de BritoCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0002-3355-1736
Monica Santin Zanatta SchindlerCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0001-6710-2229
Cássia Alves Lima-RezendeCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0001-7615-7635
Jacir Dal MagroCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0002-6465-6661
Renan de Souza RezendeCommunitarian University of Chapecó Region - Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0002-4129-0863

Funding

Conselho Nacional de Desenvolvimento Cientfico e TecnolgicoFundao de Amparo Pesquisa e Inovao do Estado de Santa Catarina
6 · The paper itself

Abstract

backgroundUrban leaf litter accumulating in water-filled containers may function as either a resource or a stressor for Aedes aegypti larvae, yet the chemical and botanical drivers of these contrasting effects remain poorly understood. We combined untargeted metabolite profiling with factorial life-history bioassays to examine how leachates from two dominant street trees, Tipuana tipu and Handroanthus heptaphyllus, influence mosquito life story. First-instar larvae were exposed to 25%, 50% or 100% leachate aged 7 or 14 days.

resultsThe T. tipu leachates were defined by persistent oxalic acid (cyclohexyl hexyl ester) and condensed tannins over 14 days of decay, whereas H. heptaphyllus rapidly lost most phenolics within the first week, shifting to profiles dominated by short-chain alkenes. At 25% dilution, T. tipu reduced mortality to 7% and produced adults with greater wing lengths than controls. However, mortality was >90% in the 50% and 100% T. tipu treatments, independent of leachate age. By contrast, H. heptaphyllus never produced mortality > 16% across all concentration-age combinations. Adult body size responded nonlinearly, with 100% T. tipu aged 14 days generated the smallest adults, whereas the largest adults emerged from 25% T. tipu.

conclusionThese results indicate that T. tipu can shift from a nutritional subsidy to a potent chemical stressor depending on concentration and aging, whereas H. heptaphyllus exerts consistently mild effects. Urban leaf litter therefore represents an overlooked but influential driver of mosquito performance in city environments. © 2026 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AedesFertilizersInsecticidesPlant LeavesAnimalsCitiesLarvaMosquito ControlFertilizersInsecticidesallelopathyintegrated pest managementphenotypic plasticitysecondary metabolitesurban ecology

Identifiers

PMID41480725
PMCPMC12976191

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.