Evidence map›Paper›PMID 41480635›Full record

ArticleRadiology case reports2026

Vertebral body osteonecrosis: Evolving imaging features over time.

Federica Masino, Valentina Cianci, Chiara Locorotondo, Andrea Torrente, Gabriele Fanigliulo, Antonio Serinelli, Marina Balbino, Manuela Montatore, Eluisa Muscogiuri, Giuseppe Guglielmi

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PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Federica MasinoDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, Foggia, FG 71122, Italy.
Valentina CianciRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Chiara LocorotondoRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Andrea TorrenteRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Gabriele FanigliuloRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Antonio SerinelliRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Marina BalbinoDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, Foggia, FG 71122, Italy.
Manuela MontatoreDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, Foggia, FG 71122, Italy.
Eluisa MuscogiuriRadiology Unit, "A. Perrino" Hospital, Strada Statale 7 per Mesagne, Brindisi, BR 72100, Italy.
Giuseppe GuglielmiDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, Foggia, FG 71122, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 55-year-old woman with a history of multiple myeloma, osteoporosis, and long-term corticosteroid therapy, who presented with progressively worsening back pain. Imaging was pivotal for diagnosis and management. Magnetic resonance imaging (MRI) and computed tomography (CT) documented vertebral body osteonecrosis (VBON) occurring at different times and vertebral levels. In May 2024, MRI showed a fluid-filled intravertebral cleft within the L1 vertebral body, without collapse. Retrospective comparison with prior examinations (MRI and CT from 2019) demonstrated earlier VBON lesions at L4, progressing from fluid to gas phase, and a chronic collapse at T12. This case emphasizes the multifocal and temporal nature of VBON and highlights the teaching value of imaging, particularly MRI and CT, in distinguishing early osteonecrosis from neoplastic or purely osteoporotic fractures.

Indexed as

Imaging diagnosisKummel diseaseMultiple myelomaVertebral osteonecrosis

Identifiers

PMID41480635
PMCPMC12754349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.