ReviewNeuroImmune pharmacology and therapeutics2025
HIV-associated sensory neuropathy: current progress and future challenges.
Review in NeuroImmune pharmacology and therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
Currently, no US Food and Drug Administration-approved treatments exist to manage HIV-associated sensory neuropathy (HIV-SN) and management is largely confined to adjusting antiretroviral therapy (ART) doses and medications. Thus, this urgent health crisis requires strong research commitment to identify a cure or palliative treatment. This review explores the current state-of-the-art related to HIV-SN. It first explores recent developments in the understanding of HIV-SN, emphasizing the importance of developments in the HIV-SN mouse model and non-myelination intra epidermal never fiber denervation. Next, the neurotoxic side effects of ART are summarized. Finally, we explore the interactions and synergy between HIV-SN and ART in the pathogenesis of peripheral neuropathy. While the overall mortality related to HIV has decreased significantly in recent decades, further elucidation of the exact mechanisms of HIV-SN is needed to better treat patients living with HIV as a chronic condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.