SynthesisFrontiers in medicine2025
A meta-analysis of the effects of multimodal intervention measures on the recovery of postpartum women after cesarean section.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Object: This systematic review and meta-analysis evaluated whether multimodal intervention bundles improve recovery after cesarean section compared with routine care. Methods: Following PRISMA 2020, we searched PubMed, Embase, Scopus, Web of Science, and major Chinese databases (CNKI, Wanfang, VIP) from inception to July 2025 without language restrictions. Eligible randomized controlled trials enrolled postpartum women undergoing cesarean section and implemented bundles comprising ≥2 distinct domains (e.g., opioid-sparing analgesia, early mobilization, early oral intake/nutrition or breastfeeding support, structured nursing, psychological education). The primary endpoint was pain intensity at 24 h (VAS); secondary endpoints included pain at other time points, analgesic consumption, time to first ambulation and first flatus, adverse events, length of stay, breastfeeding initiation/time, and maternal psychological recovery. Relative risks were pooled for dichotomous outcomes and mean (or standardized mean) differences for continuous outcomes, using random effects when heterogeneity was substantial. Results: Twelve RCTs ( Conclusion: Collectively, the current evidence suggests that multimodal, ERAS-oriented care pathways may facilitate safer and more rapid early recovery following cesarean section, particularly by enhancing analgesic efficacy, mobilization, and gastrointestinal function. Nevertheless, the marked heterogeneity in bundle composition, implementation intensity, and outcome definitions, together with the single-country evidence base and moderate risk of bias, substantially limits the certainty and generalizability of these findings.
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