ReviewWorld journal of orthopedics2025
Platelet rich plasma applications in orthopedics: A review of recent advances.
Review in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comparative effects of platelets and plasma-derived mitochondria in early-phase Achilles tendon inflammation.Regenerative biomaterials · 2026Article
- Platelet-Rich Plasma: Are We Ahead of the Evidence?The archives of bone and joint surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Platelet-rich plasma (PRP) therapy has gained prominence in orthopedics as a regenerative approach that utilizes autologous platelets enriched with growth factors to facilitate tissue healing. Innovations such as protein-enriched filtered PRP and the integration of PRP with biomaterials, including 3D-printed scaffolds and bioactive molecules like kartogenin, have been developed to enhance outcomes in cartilage and bone repair. Clinical studies have demonstrated the efficacy of PRP in managing conditions such as knee osteoarthritis, rotator cuff tendinopathy, and lateral epicondylitis, often showing superior long-term benefits compared with conventional treatments. Emerging therapies that combine PRP with mesenchymal stem cells and peptide-based treatments have shown synergistic effects, further enhancing tissue regeneration and functional recovery. Despite these promising developments, variability in PRP preparation methods and application protocols underscores the need for standardized guidelines and large-scale clinical trials to fully establish the role of PRP in orthopedic practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.