Evidence map›Paper›PMID 41480446›Full record

ArticleCureus2025

A Pyogenic Liver Abscess in the Setting of Fontan-Associated Liver Disease.

Thomas J Mason, John A Gambril, Joshua Spegman, Matthew Laubham

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas J MasonInternal Medicine - Pediatrics, The Ohio State University, Nationwide Children's Hospital, Columbus, USA.
John A GambrilCardiology, University of Alabama at Birmingham School of Medicine, Birmingham, USA.
Joshua SpegmanInternal Medicine - Pediatrics, The Ohio State University, Nationwide Children's Hospital, Columbus, USA.
Matthew LaubhamAdult Congenital Heart Disease, The Ohio State University, Nationwide Children's Hospital, Columbus, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Fontan procedure is widely used today in the surgical management of congenital heart disease as the final step in single ventricle palliation pathways. It is associated with unique complications, most notably Fontan-associated liver disease (FALD), which is a condition arising from the unique hemodynamics of the Fontan circulation that occurs universally after the procedure. Though varying in severity from mild hepatocellular liver injury to frank decompensated cirrhosis, FALD progresses at different rates depending on the patient. Given the significant morbidity and mortality associated with late-stage FALD, a better understanding of the pathophysiology and complications is needed. Here we describe a unique case of a pyogenic liver abscess in a patient with FALD, possibly the first reported in the literature.

Indexed as

adult congenital heart disease (achd)congenital heart diseases (chds)congestive hepatopathyfontan-associated liver diseasefontan circulationfontan physiologypyogenic liver abscess (pla)

Identifiers

PMID41480446
PMCPMC12755862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.