Evidence map›Paper›PMID 41480444›Full record

ArticleCureus2025

Challenges and Outcomes of Three Years of the Adhesive Intestinal Obstruction Management Protocol.

Moataz M Ewedah, Dixon Osilli, Praveen Surya Ravichandran, Tarun Sai Krishna Puli, Faris A Abbadi, Tanya Krasteva, Sayed Haschmat Sarwary

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moataz M EwedahSurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Dixon OsilliSurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Praveen Surya RavichandranSurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Tarun Sai Krishna PuliPaediatrics and Child Health, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Faris A AbbadiSurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Tanya KrastevaSurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.
Sayed Haschmat SarwarySurgery, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmall bowel obstruction (SBO) is a significant contributor to surgical morbidity, mortality, and healthcare costs, contributing to a significant number of emergency laparotomies. Advancements in diagnostic techniques have improved the accuracy in delineating simple from complicated SBOs. Some adhesive SBOs will ultimately need surgical intervention, mostly when they are complicated cases. Recently, minimally invasive surgeries, enhanced recovery protocols, and multidisciplinary approaches have become more popular in optimising recovery and minimising recurrence risks. On the other hand, most adhesive SBOs can be managed conservatively with bowel rest, nasogastric (NG) decompression, intravenous fluid therapy, and water-soluble oral contrast agents, leading to a significant reduction in operation-related morbidity, hospital stays, and healthcare costs. Current guidelines recommend a trial of conservative management, although not without controversy.

aimThis study aimed to explain the predictive factors of success or failure of treatments of adhesive SBOs and statistically report the effect of co-morbidities and expected outcomes of SBO management, based on three-year data from a single high-volume centre in London, UK. METHODOLOGY: Our retrospective-descriptive study included patients with clinical signs of SBO, older than 16 years old, and CT proving adhesive SBO, who required hospital admission. We excluded patients with other causes of SBO and those who had no CT evidence of adhesive disease. Data were collected from online hospital records and analysed in Microsoft Excel® (Microsoft Corporation, Redmond, Washington). Hospital protocol was NG decompression for at least six hours in uncomplicated cases, followed by oral or NG Gastrografin, with abdominal X-rays taken at six and 12 hours post-Gastrografin intake to assess contrast in the colon or rectum. Successful cases were then given a trial of oral feeds before discharge. Those with no contrast in the large intestine, persistent abdominal pain, and onset abdominal tenderness or peritonitis were taken to surgery. RESULTS AND LIMITATIONS: Out of 415 patients, 30.4% required surgery either as initial mode of treatment or after failed conservative management, proving the effectivity of therapeutic Gastrografin (69.6%), followed by 35.2% being 75 or less years old, proving SBO is more prevalent in elderly population with co-morbidities, as 40.5% are ASA Grade 3, prone to post-operative complications. Surprisingly, COPD patients required surgery more often than those who did not have it, as they desaturate due to distension easily. On the other hand, not much statistical difference is seen in the 30-day mortality rate between the operated and conservatively managed groups.

conclusionOur study aligns with the literature to prove that our management protocol is safe. Alongside, the post-operative burden of those undergoing surgery is high; it is vital to identify complex patients for surgery to reduce mortality and morbidity. This goes hand in hand with weighing risks and benefits. Elderly patients carry the risk of major complications plus a higher mortality rate. Timely intervention with therapeutic Gastrografin can minimise the hospital stay and the costs for the NHS owing to long stay post-operatively.

Indexed as

acute small bowel obstructionadhesiolysisasbogastrografinnasogastric tube (ngt)sbosmall-bowel obstruction

Identifiers

PMID41480444
PMCPMC12755942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.